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产后11年垂体影像显现:晚期席汉综合征一例报告

Unmasking the pituitary shadow 11 years postpartum: A case report of late-stage Sheehan's syndrome.

作者信息

Mesbah Oumaima, Messaoud Ola, Kabila Badr, El Aoufir Omar, Jroundi Laila, Houssaini Zaynab Iraqi

机构信息

Emergency Radiology Department, Ibn Sina University Hospital, Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Rabat, Morocco.

出版信息

Radiol Case Rep. 2025 Apr 12;20(7):3267-3270. doi: 10.1016/j.radcr.2025.03.027. eCollection 2025 Jul.

Abstract

Sheehan's syndrome (SS) is a rare but significant condition that occurs as a result of postpartum pituitary gland infarction, typically following severe blood loss or hypotension during or after childbirth. The syndrome is characterized by signs of anterior pituitary insufficiency, including deficiencies in hormones such as cortisol, thyroid hormones, and gonadotropins. The diagnosis of this rare but potentially fatal disease is often delayed due to the vague symptoms and the insidious nature of pituitary dysfunction. It is typically confirmed through hormonal assays and imaging, which reveal anatomical changes in the pituitary gland, such as atrophy or empty sella syndrome, supporting the diagnosis. Treatment of Sheehan's syndrome primarily involves hormone replacement therapy to correct the endocrine imbalances, to prevent adrenal crises and other complications. We present the case of a 40-year-old woman, 11 years postpartum, who was hospitalized for a severe infection, revealing a pituitary dysfunction due to a delayed revelation of Sheehan's syndrome.

摘要

席汉综合征(SS)是一种罕见但严重的病症,它是产后垂体梗死的结果,通常发生在分娩期间或之后的严重失血或低血压之后。该综合征的特征是垂体前叶功能减退的体征,包括皮质醇、甲状腺激素和促性腺激素等激素缺乏。由于症状模糊以及垂体功能障碍的隐匿性,这种罕见但可能致命的疾病的诊断常常延迟。通常通过激素检测和影像学检查来确诊,这些检查可揭示垂体的解剖学变化,如萎缩或空蝶鞍综合征,从而支持诊断。席汉综合征的治疗主要包括激素替代疗法,以纠正内分泌失衡,预防肾上腺危象和其他并发症。我们报告一例产后11年的40岁女性病例,该患者因严重感染住院,结果发现因席汉综合征发现延迟而导致垂体功能障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/347e/12018080/3538f51bf392/gr1.jpg

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