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产后六年席汉综合征一例,伴肾上腺危象,并发甲状腺功能减退和大量心包积液。

A Case of Sheehan Syndrome Six Years Postpartum Presented With Adrenal Crisis and Complicated by Hypothyroidism and Massive Pericardial Effusion.

作者信息

Mishra Priya, Jindal Himanshu, Khan Efa, Palawat Sandeep S

机构信息

Department of Internal Medicine, Ganesh Shankar Vidyarthi Memorial Medical College, Kanpur, IND.

出版信息

Cureus. 2023 Jan 19;15(1):e33972. doi: 10.7759/cureus.33972. eCollection 2023 Jan.

DOI:10.7759/cureus.33972
PMID:36824567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9941025/
Abstract

Sheehan syndrome is often a sequela of massive postpartum hemorrhage in resource-poor healthcare settings where blood loss during delivery is often neglected. The diagnosis of this rare but fatal disease is often delayed because the symptoms are vague and the pituitary dysfunction is insidious in nature. We report the case of a 35-year-old multiparous female with anhedonia and raised serum transaminases. She presented with constitutional symptoms. Her last vaginal delivery, six years back, was the last obstetric event that yielded a stillbirth child. She had had amenorrhea since then. Upon further evaluation, she was found to have a massive pericardial effusion, hypopituitarism, and a partially empty sella. This case report highlights the uncharacteristic symptoms that a patient presents with which ultimately lead to delayed diagnosis. Early diagnosis can go miles in improving the quality of life of the patient besides saving the patient from an adrenal crisis.

摘要

希恩综合征通常是资源匮乏的医疗环境中产后大出血的后遗症,在这种环境下,分娩期间的失血往往被忽视。这种罕见但致命疾病的诊断常常延迟,因为症状模糊,垂体功能障碍本质上隐匿。我们报告一例35岁多产女性病例,该患者有快感缺失及血清转氨酶升高。她有全身症状。她最后一次阴道分娩是在六年前,那次分娩产出一名死产儿,此后她一直闭经。经进一步评估,发现她有大量心包积液、垂体功能减退和部分空蝶鞍。本病例报告强调了患者出现的非典型症状最终导致诊断延迟。早期诊断除了能使患者免于肾上腺危象外,还能极大地改善患者生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ca/9941025/4656893737fa/cureus-0015-00000033972-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ca/9941025/bdb83e9a6461/cureus-0015-00000033972-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ca/9941025/5b26495510f2/cureus-0015-00000033972-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ca/9941025/4656893737fa/cureus-0015-00000033972-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ca/9941025/bdb83e9a6461/cureus-0015-00000033972-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ca/9941025/5b26495510f2/cureus-0015-00000033972-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ca/9941025/4656893737fa/cureus-0015-00000033972-i03.jpg

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本文引用的文献

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Sheehan Syndrome: An Unusual Presentation Without Inciting Factors.希恩综合征:一种无诱发因素的不典型表现。
Womens Health Rep (New Rochelle). 2020 Aug 24;1(1):287-292. doi: 10.1089/whr.2019.0028. eCollection 2020.
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Pericardial diseases in patients with hypothyroidism.甲状腺功能减退症患者的心包疾病。
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Post-Partum Necrosis of the Anterior Pituitary.垂体前叶产后坏死
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A case of acute Sheehan's syndrome and literature review: a rare but life-threatening complication of postpartum hemorrhage.1例急性希恩综合征病例及文献复习:产后出血罕见但危及生命的并发症
BMC Pregnancy Childbirth. 2017 Jun 14;17(1):188. doi: 10.1186/s12884-017-1380-y.
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Imaging of Neurologic Conditions in Pregnant Patients.孕期患者神经系统疾病的影像学检查
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Recurrent hypoglycaemia: a delayed presentation of Sheehan syndrome.复发性低血糖症:席汉综合征的延迟表现。
BMJ Case Rep. 2014 May 19;2014:bcr2013200991. doi: 10.1136/bcr-2013-200991.
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