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用于治疗成骨不全症中长骨干骺端和骨干骨折及畸形的钢板:一项范围综述。

Plates for the treatment of long bone metaphyseal and diaphyseal fracture and deformity in osteogenesis imperfecta: A scoping review.

作者信息

Louni Yacine, Hamdy Reggie

机构信息

McGill University, Montreal, QC, Canada.

Shriners Hospitals for Children Canada, Montreal, QC, Canada.

出版信息

J Child Orthop. 2025 Apr 24:18632521251332498. doi: 10.1177/18632521251332498.

DOI:10.1177/18632521251332498
PMID:40292352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12031734/
Abstract

PURPOSE

Osteogenesis imperfecta is a rare disorder characterized by bone fragility. The current gold standard treatment for long bone fractures and deformities is telescopic intramedullary rods. Although the use of plates as a standalone implant has been discouraged, recent research has investigated their use as an adjunct to intramedullary fixation. This scoping review aims to assess the current literature on plates for the treatment of long bone metaphyseal and diaphyseal fractures and deformities in osteogenesis imperfecta.

METHODS

The MEDLINE, Embase, CENTRAL, and CDSR databases were searched via PubMed, Ovid, and Cochrane. Titles and abstracts of studies were screened, followed by full assessment of selected articles. Studies included were peer-reviewed, published in English in the last 20 years, and investigated plating alone or combined with other implants for the treatment of metaphyseal or diaphyseal long bone fractures and deformities in osteogenesis imperfecta.

RESULTS

Eleven articles were included: four investigated plating alone, two compared different implants, and five assessed plating as an adjunct to intramedullary fixation.

CONCLUSIONS

Using plates alone is not recommended due to the high rate of complications, implant-related complications, and revision surgeries. However, they can be used when deemed appropriate by the surgeon or in narrow canals. Overall, the use of plates as an adjunct to intramedullary nails shows promising results, although further research is required to determine the indications for additional plating and the best timing of plate removal.

LEVEL OF EVIDENCE

Level III (scoping review).

摘要

目的

成骨不全是一种以骨脆性为特征的罕见疾病。目前治疗长骨骨折和畸形的金标准是可伸缩髓内钉。尽管不鼓励单独使用钢板作为植入物,但最近的研究探讨了其作为髓内固定辅助手段的应用。本综述旨在评估目前关于钢板治疗成骨不全患者长骨干骺端和骨干骨折及畸形的文献。

方法

通过PubMed、Ovid和Cochrane检索MEDLINE、Embase、CENTRAL和CDSR数据库。筛选研究的标题和摘要,随后对选定文章进行全面评估。纳入的研究需经过同行评审,在过去20年以英文发表,并研究了单独使用钢板或与其他植入物联合使用治疗成骨不全患者的干骺端或骨干长骨骨折及畸形。

结果

纳入11篇文章:4篇研究单独使用钢板,2篇比较不同植入物,5篇评估钢板作为髓内固定的辅助手段。

结论

由于并发症发生率高、与植入物相关的并发症以及翻修手术,不建议单独使用钢板。然而,在外科医生认为合适时或在狭窄髓腔内可使用钢板。总体而言,钢板作为髓内钉的辅助手段显示出有前景的结果,尽管需要进一步研究以确定额外使用钢板的适应证和最佳取出时机。

证据级别

三级(综述)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86af/12202890/5d64ac5d7382/10.1177_18632521251332498-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86af/12202890/5d64ac5d7382/10.1177_18632521251332498-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86af/12202890/5d64ac5d7382/10.1177_18632521251332498-fig1.jpg

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本文引用的文献

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J Pediatr Orthop. 2025 Mar 1;45(3):e291-e298. doi: 10.1097/BPO.0000000000002860. Epub 2024 Oct 31.
2
Surgical treatment of osteogenesis imperfecta: a summary of the incidence of femoral implant-related complications in children with Sillence type I, III and IV.手术治疗成骨不全症:Sillence Ⅰ型、Ⅲ型和Ⅳ型患儿股骨植入物相关并发症发生率总结。
Int Orthop. 2024 Jun;48(6):1645-1655. doi: 10.1007/s00264-024-06113-8. Epub 2024 Feb 22.
3
Fixation techniques in lower extremity correction osteotomies and fractures in mild-to-severe osteogenesis imperfecta patients: evaluation of the results and complications.
下肢矫正截骨术和中重度成骨不全症患者骨折固定技术:疗效和并发症评估。
J Orthop Surg Res. 2023 Jun 16;18(1):437. doi: 10.1186/s13018-023-03917-z.
4
Which is the best femoral implant in children with osteogenesis imperfecta? a retrospective cohort study of 783 procedures.哪种股骨植入物最适合成骨不全症患儿?783 例回顾性队列研究。
BMC Musculoskelet Disord. 2023 Feb 9;24(1):110. doi: 10.1186/s12891-023-06222-2.
5
Steps for Conducting a Scoping Review.进行范围综述的步骤。
J Grad Med Educ. 2022 Oct;14(5):565-567. doi: 10.4300/JGME-D-22-00621.1.
6
Case Report: Locking Plate for Cubitus Varus Correction in a 7-Year-Old Girl With Osteogenesis Imperfecta.病例报告:用于一名7岁成骨不全女童肘内翻矫正的锁定钢板
Front Pediatr. 2022 Jan 12;9:781703. doi: 10.3389/fped.2021.781703. eCollection 2021.
7
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.PRISMA 2020 声明:系统评价报告的更新指南。
BMJ. 2021 Mar 29;372:n71. doi: 10.1136/bmj.n71.
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