Maffei L, Fiorentini A, Bisti S, Holländer H
Exp Brain Res. 1985;59(2):423-5. doi: 10.1007/BF00230925.
Electroretinographic responses (ERG) to homogeneous light flashes and to alternating gratings were recorded from either eye of monkeys in which one optic nerve had been previously sectioned. Three weeks after optic nerve section the ERG response of the operated eye to alternating gratings was drastically reduced in amplitude and 5 weeks after surgery it was reduced to noise level. The uniform field ERG was unaffected. Histological examination of whole-mounted retinas of monkeys sacrificed 6 and 8 weeks after optic nerve section showed a loss of ganglion cells in the operated eye. It is concluded that the integrity of ganglion cells is essential for the generation of a normal ERG response to gratings.
在先前已切断一侧视神经的猴子的任意一只眼睛中，记录了对均匀光闪烁和交替光栅的视网膜电图反应（ERG）。视神经切断三周后，手术眼对交替光栅的ERG反应幅度急剧降低，术后五周降至噪声水平。均匀视野ERG未受影响。对视神经切断后6周和8周处死的猴子的整个视网膜进行组织学检查，结果显示手术眼的神经节细胞缺失。得出的结论是，神经节细胞的完整性对于产生对光栅的正常ERG反应至关重要。
