The Effectiveness of Live Birth Rate of Traditional Chinese Medicine Intervention for Infertile Women Undergoing a Second Round of IVF Is Influenced by Age.

BACKGROUND/AIM: While fertilization (IVF) is an effective treatment for infertility, the live birth rate remains suboptimal. This study aimed to evaluate the factors influencing live birth rates in infertile women undergoing a second round of IVF combined with traditional Chinese medicine (TCM) treatment.

PATIENTS AND METHODS

This was a single-center, retrospective cohort study involving 45 infertile women undergoing a second round of IVF who underwent a combined treatment approach integrating TCM with IVF. Clinical factors affecting live birth rates were analyzed using Student's test, Pearson's Chi-square test, and univariate logistic regression models.

RESULTS

The findings revealed a clinical pregnancy rate of 51.11% and a live birth rate of 42.22%, underscoring the potential effectiveness of combining TCM with a second round of IVF for infertile women. Additionally, maternal age showed a statistically significant influence on the clinical pregnancy rate (39.32±2.93 years 36.48±2.47 years, =0.005) and live birth rate (39.68±2.85 years 35.58±2.95 years, <0.001).

CONCLUSION

Integrating traditional Chinese medicine into IVF protocols notably enhances maternal success rates. For women over 38, age-specific strategies such as fertility preservation, optimized ovarian stimulation, advanced embryo selection, and oocyte donation are key to addressing age-related challenges.