Zhang Hui-Ping, Yi Qian, Guan Xin-Yu, Dai Rui-Rong, Pang Jie, Zhong Qing, Tan Shaozao, Luo Dong, Li Yan Yan, Xie Mo, Zhou Xiao-Ping, Li Dan
College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry, Jinan University, Guangzhou, 510632, China.
Institute of Medical Microbiology, Department of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
Angew Chem Int Ed Engl. 2025 Jul;64(27):e202507349. doi: 10.1002/anie.202507349. Epub 2025 May 8.
Singlet oxygen (O) is a widely used reactive oxygen species (ROS), making the development of new materials capable of efficiently generating it highly important. In this work, we report a series of isostructural metal-organic frameworks (MOFs), named JNU-300 (JNU = Jinan University), can spontaneously generate O by directly activating triplet oxygen (O) from the air without the need for additional light irradiation. The highly selective generation of O by JNU-300 is verified by electron paramagnetic resonance (EPR) spectroscopy and probe experiments for O. The generated O can be employed for aerobic oxidation of sulfide and antibacterial application. Mechanism studies revealed that the framework structure, and the adsorption and polarization of O by the coordination units of JNU-300, are crucial for the O generation. To the best of our knowledge, MOFs JNU-300 are the first MOF material capable of producing O by activating O in the absence of light at room temperature. This work provides new insights into the design and construction of functional MOF materials capable of generating O via activating O without light irradiation, opening new possibilities for their application in specialized fields that require O in the dark.
单线态氧（O）是一种广泛使用的活性氧（ROS），因此开发能够高效生成单线态氧的新材料具有极其重要的意义。在这项工作中，我们报道了一系列同构的金属有机框架（MOF），命名为JNU-300（JNU = 暨南大学），它们能够通过直接激活空气中的三线态氧（O）自发产生单线态氧，无需额外的光照。通过电子顺磁共振（EPR）光谱和单线态氧的探针实验验证了JNU-300对单线态氧的高选择性生成。所生成的单线态氧可用于硫化物的需氧氧化和抗菌应用。机理研究表明，框架结构以及JNU-300的配位单元对三线态氧的吸附和极化作用对于单线态氧的生成至关重要。据我们所知，MOF材料JNU-300是第一种能够在室温下无光条件下通过激活三线态氧来产生单线态氧的MOF材料。这项工作为设计和构建能够在无光照条件下通过激活三线态氧生成单线态氧的功能性MOF材料提供了新的见解，为其在黑暗中需要单线态氧的特殊领域的应用开辟了新的可能性。
