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成年男性尿道狭窄的可视内部尿道切开术长期效果不佳。

Visual Internal Urethrotomy for Adult Male Urethral Stricture Has Poor Long-Term Results.

作者信息

Al Taweel Waleed, Seyam Raouf

机构信息

Department of Urology, King Faisal Hospital and Research Center, Riyadh 11211, Saudi Arabia.

Department of Urology, King Faisal Hospital and Research Center, Riyadh 11211, Saudi Arabia ; Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

出版信息

Adv Urol. 2015;2015:656459. doi: 10.1155/2015/656459. Epub 2015 Oct 1.

Abstract

Objective. To determine the long-term stricture-free rate after visual internal urethrotomy following initial and follow-up urethrotomies. Methods. The records of all male patients who underwent direct visual internal urethrotomy for urethral stricture disease in our hospital between July 2004 and May 2012 were reviewed. The Kaplan-Meier method was used to analyze stricture-free probability after the first, second, third, fourth, and fifth urethrotomies. Results. A total of 301 patients were included. The overall stricture-free rate at the 36-month follow-up was 8.3% with a median time to recurrence of 10 months (95% CI of 9.5 to 10.5, range: 2-36). The stricture-free rate after one urethrotomy was 12.1% with a median time to recurrence of eight months (95% CI of 7.1-8.9). After the second urethrotomy, the stricture-free rate was 7.9% with a median time to recurrence of 10 months (95% CI of 9.3 to 10.6). After the third to fifth procedures, the stricture-free rate was 0%. There was no significant difference in the stricture-free rate between single and multiple procedures. Conclusion. The long-term stricture-free rate of visual internal urethrotomy is modest even after a single procedure.

摘要

目的。确定初次及后续尿道内切开术后经直视尿道内切开术的长期无狭窄率。方法。回顾性分析2004年7月至2012年5月间在我院因尿道狭窄疾病接受直接直视尿道内切开术的所有男性患者的病历。采用Kaplan-Meier法分析首次、第二次、第三次、第四次和第五次尿道内切开术后的无狭窄概率。结果。共纳入301例患者。36个月随访时的总体无狭窄率为8.3%,复发的中位时间为10个月(95%CI为9.5至10.5,范围:2 - 36个月)。一次尿道内切开术后的无狭窄率为12.1%,复发的中位时间为8个月(95%CI为7.1 - 8.9)。第二次尿道内切开术后,无狭窄率为7.9%,复发的中位时间为10个月(95%CI为9.3至10.6)。第三次至第五次手术后,无狭窄率为0%。单次手术与多次手术的无狭窄率无显著差异。结论。即使是单次手术,直视尿道内切开术的长期无狭窄率也不高。

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