Winkelmann Michael, Kassube Matthias, Rübenthaler Johannes, Sheikh Gabriel T, Kunz Wolfgang G
Klinik und Poliklinik für Radiologie, LMU Klinikum, Marchioninistr. 15, 81377, München, Deutschland.
LMU KlinikumDeutsches Zentrum für Translationale Krebsforschung (DKTK) and Bayerisches Zentrum für Krebsforschung (BZKF), Partnereinrichtung München, München, Deutschland.
Radiologie (Heidelb). 2025 Apr 28. doi: 10.1007/s00117-025-01447-9.
CLINICAL/METHODOLOGICAL ISSUE: Imaging procedures are an integral component of the diagnostics and treatment of lymphomas for the initial diagnosis, staging and assessment of the efficacy of treatment. The different lymphoma entities show differences in metabolic activity and therefore require different examination modalities.
This review article focuses on the primary imaging diagnostics of lymphomas using computed tomography (CT), positron emission tomography (PET)/CT and magnetic resonance imaging (MRI). It also discusses the special imaging features of the various subtypes.
The potential of whole-body (WB) MRI, PET/MRI and other PET tracers are discussed.
In addition, the most important classifications for the diagnosis of spread and diagnostic scores based on imaging are explained and important pitfalls in initial imaging are discussed.
Besides these most frequently used modalities, WB MRI and PET/MRI offer alternatives for special patient groups (e.g., children and pregnant women).
Imaging in the initial diagnosis of lymphomas should generally include an examination of the neck, thorax, abdomen, pelvis and inguinal region. Depending on the lymphoma entity, imaging is often performed using PET/CT or CT. Standardized staging classifications are used for many lymphoma entities but there are adapted criteria for several subtypes that should be taken into consideration.
临床/方法学问题:成像检查是淋巴瘤诊断和治疗的重要组成部分,用于初始诊断、分期及治疗效果评估。不同类型的淋巴瘤在代谢活性方面存在差异,因此需要不同的检查方式。
本文综述聚焦于利用计算机断层扫描(CT)、正电子发射断层扫描(PET)/CT和磁共振成像(MRI)对淋巴瘤进行的初步成像诊断。还讨论了各种亚型的特殊成像特征。
探讨了全身(WB)MRI、PET/MRI及其他PET示踪剂的潜力。
此外,还解释了基于成像诊断扩散的最重要分类和诊断评分,并讨论了初始成像中的重要陷阱。
除了这些最常用的检查方式外,WB MRI和PET/MRI为特殊患者群体(如儿童和孕妇)提供了替代选择。
淋巴瘤初始诊断中的成像检查通常应包括对颈部、胸部、腹部、骨盆和腹股沟区的检查。根据淋巴瘤的类型,成像检查通常采用PET/CT或CT。许多淋巴瘤类型使用标准化的分期分类,但几种亚型有适用标准,应予以考虑。