Huguet-Feixa Agnes, Artigues-Barberà Eva, Sol Joaquim, Gomez-Arbones Xavier, Godoy Pere, Bravo Marta Ortega
CAP Rambla Ferran, Gerència Territorial de Lleida, Institut Català de la Salut, Rambla Ferran, 44, Atenció Primària, Lleida, 25007, Spain.
Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIA-PJGol), Gran Via de les Corts Catalanes, 587, Barcelona, 08007, Spain.
BMC Prim Care. 2025 Apr 28;26(1):132. doi: 10.1186/s12875-025-02820-2.
Vaccine refusal and hesitancy represent a crucial challenge to public health, causing delays in vaccination and compromising herd immunity.
To address this issue, we conducted a comprehensive observational study on the adult Spanish population in 2021. Using an online questionnaire, we examined the sociodemographic and sociocultural factors, beliefs, and opinions of those refusing or hesitant about vaccines, as well as their vaccination behaviors by vaccine type and sex.
There were 1,312 respondents: 74.5% were female, 73.7% were between 31 and 59 years old, and 71.0% had university studies. Our findings revealed that vaccine refusal rates were relatively low (16.8%), and mainly associated with influenza vaccination (10.3%). Higher refusal rates were observed in those over 60 years old, those expressing hesitancy due to vaccine components, those opposing free and compulsory vaccination, those unaware that vaccination protects the community, and those against consuming cow's milk and using infant formulas for breastfeeding. Vaccine hesitancy was greatest in individuals under 31 years old, women, parents of children under 15 years old, against compulsory vaccination, unaware that vaccination protects the community, with hesitancy due to vaccine costs, and in favour of alternative and complementary treatments.
These insights highlight the need for strategies to improve education about vaccination and dispel misconceptions, which are crucial for effectively reducing vaccine refusal and hesitancy across the population.
疫苗拒绝和犹豫对公共卫生构成了重大挑战,导致疫苗接种延迟并损害群体免疫。
为解决这一问题,我们于2021年对西班牙成年人群体进行了一项全面的观察性研究。通过在线问卷,我们调查了拒绝或犹豫接种疫苗者的社会人口学和社会文化因素、信念及观点,以及他们按疫苗类型和性别的接种行为。
共有1312名受访者:74.5%为女性,73.7%年龄在31至59岁之间,71.0%拥有大学学历。我们的研究结果显示,疫苗拒绝率相对较低(16.8%),且主要与流感疫苗接种(10.3%)相关。60岁以上人群、因疫苗成分而表示犹豫者、反对免费和强制接种者、未意识到接种疫苗可保护社区者,以及反对饮用牛奶和使用婴儿配方奶粉进行母乳喂养者的拒绝率较高。31岁以下人群、女性、15岁以下儿童的父母、反对强制接种、未意识到接种疫苗可保护社区、因疫苗成本而犹豫,以及支持替代和补充疗法的人群中,疫苗犹豫情绪最为严重。
这些见解凸显了制定策略以加强疫苗接种教育并消除误解的必要性,这对于有效减少全体人群中的疫苗拒绝和犹豫情况至关重要。