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疫苗接种依从性:从疫苗犹豫到实际接种以及一组产后母亲拒绝儿童疫苗接种的原因

Vaccine Adherence: From Vaccine Hesitancy to Actual Vaccination and Reasons for Refusal of Childhood Vaccines in a Group of Postpartum Mothers.

作者信息

Iova Camelia Florina, Daina Lucia Georgeta, Ilea Codrin Dan Nicolae, Domnariu Horaţiu Paul, Ghitea Timea Claudia, Daina Mădălina Diana

机构信息

Faculty of Medicine and Pharmacy, Doctoral School, University of Oradea, Oradea, Romania.

Doctoral School, University of Medicine and Pharmacy "Iuliu Haţieganu" Cluj Napoca, Cluj-Napoca, Romania.

出版信息

In Vivo. 2025 Jan-Feb;39(1):509-523. doi: 10.21873/invivo.13855.

DOI:10.21873/invivo.13855
PMID:39740905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11705103/
Abstract

BACKGROUND/AIM: Vaccine refusal or delay remains a significant public health concern, leading to lower vaccination rates and increasing the risk of preventable diseases.

PATIENTS AND METHODS

The study included 404 mothers and 413 children, assessing vaccination coverage and conducting telephone interviews with mothers who declined vaccines to understand their reasons.

RESULTS

Children of mothers who supported vaccination were more likely to be fully immunized compared to those with hesitant mothers. Among the incompletely vaccinated or unvaccinated children, 73.08% had mothers from the hesitant group (GNV). However, 90.05% of hesitant mothers still vaccinated their children with all recommended vaccines, while 9.95% maintained their refusal. Only 3.22% of the total sample, all from the GNV group, refused vaccination entirely. The primary reasons for refusal included fear of side effects, lack of trust in vaccines or the healthcare system, negative vaccination experiences, and influence from media or social platforms.

CONCLUSION

While vaccination behaviors may improve as a child grows, a significant proportion of hesitant parents continue to exist across different population groups, contributing to suboptimal vaccination coverage rates. The consistent implementation of unified, nationwide strategies aimed at increasing trust in vaccines and the vaccination process is essential for achieving protective vaccination rates.

摘要

背景/目的:疫苗拒绝或延迟接种仍是一个重大的公共卫生问题,导致疫苗接种率降低,并增加了可预防疾病的风险。

患者与方法

该研究纳入了404名母亲和413名儿童,评估疫苗接种覆盖率,并对拒绝接种疫苗的母亲进行电话访谈,以了解其原因。

结果

与母亲对疫苗接种持犹豫态度的儿童相比,母亲支持疫苗接种的儿童更有可能获得全程免疫。在未完全接种或未接种疫苗的儿童中,73.08%的儿童母亲来自犹豫组(GNV)。然而,90.05%的犹豫母亲仍为其子女接种了所有推荐疫苗,而9.95%的母亲仍拒绝接种。在全部样本中,只有3.22%(均来自GNV组)的母亲完全拒绝疫苗接种。拒绝接种的主要原因包括担心副作用、对疫苗或医疗系统缺乏信任、负面的接种经历以及来自媒体或社交平台的影响。

结论

虽然随着孩子长大,疫苗接种行为可能会有所改善,但不同人群中仍有相当比例的犹豫家长,这导致了疫苗接种覆盖率不理想。持续实施旨在增强对疫苗和接种过程信任的统一全国性策略,对于实现保护性疫苗接种率至关重要。

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本文引用的文献

1
Knowledge, Attitudes, Intentions and Vaccine Hesitancy among Postpartum Mothers in a Region from the Northwest of Romania.罗马尼亚西北部某地区产后母亲的知识、态度、意图及疫苗犹豫情况
Vaccines (Basel). 2023 Nov 21;11(12):1736. doi: 10.3390/vaccines11121736.
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Evaluation of the Knowledge and Attitude of Adolescents Regarding the HPV Infection, HPV Vaccination and Cervical Cancer in a Region from the Northwest of Romania.罗马尼亚西北部某地区青少年对人乳头瘤病毒(HPV)感染、HPV疫苗接种及宫颈癌的认知与态度评估
Patient Prefer Adherence. 2023 Sep 8;17:2249-2262. doi: 10.2147/PPA.S421875. eCollection 2023.
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Perceptions of the safety of vaccines and vaccine associated knowledge levels in Europe: A 2019 cross-sectional study in 28 countries.
欧洲对疫苗安全性的认知和疫苗相关知识水平:2019 年 28 个国家的横断面研究。
Prev Med. 2022 Jun;159:107071. doi: 10.1016/j.ypmed.2022.107071. Epub 2022 Apr 20.
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Factors influencing healthcare professionals' confidence in vaccination in Europe: a literature review.影响欧洲医疗保健专业人员疫苗接种信心的因素:文献综述。
Hum Vaccin Immunother. 2022 Dec 31;18(1):2041360. doi: 10.1080/21645515.2022.2041360. Epub 2022 Mar 15.
5
Parental Vaccine Hesitancy and Association With Childhood Diphtheria, Tetanus Toxoid, and Acellular Pertussis; Measles, Mumps, and Rubella; Rotavirus; and Combined 7-Series Vaccination.父母对接种疫苗的犹豫与儿童白喉、破伤风类毒素和无细胞百日咳、麻疹、腮腺炎和风疹、轮状病毒和联合 7 价疫苗接种的关系。
Am J Prev Med. 2022 Mar;62(3):367-376. doi: 10.1016/j.amepre.2021.08.015. Epub 2021 Dec 8.
6
Parents' Behaviors and Experiences Associated with Four Vaccination Behavior Groups for Childhood Vaccine Hesitancy.父母行为与经验与儿童疫苗犹豫四个疫苗接种行为群体相关。
Matern Child Health J. 2022 Feb;26(2):280-288. doi: 10.1007/s10995-021-03336-8. Epub 2022 Jan 7.
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Vaccine hesitancy among parents and its influencing factors: a cross-sectional study in Guangzhou, China.家长对疫苗的犹豫及其影响因素:中国广州的一项横断面研究。
Hum Vaccin Immunother. 2021 Dec 2;17(12):5153-5161. doi: 10.1080/21645515.2021.1984131. Epub 2021 Dec 10.
8
Vaccine Hesitancy and Trust in the Scientific Community in Italy: Comparative Analysis from Two Recent Surveys.意大利的疫苗犹豫与对科学界的信任:来自两项近期调查的比较分析
Vaccines (Basel). 2021 Oct 19;9(10):1206. doi: 10.3390/vaccines9101206.
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Factors associated with pediatric vaccine hesitancy of parents: a cross-sectional study in Turkey.与土耳其父母对儿童疫苗犹豫不决相关的因素:一项横断面研究。
Hum Vaccin Immunother. 2021 Nov 2;17(11):4505-4511. doi: 10.1080/21645515.2021.1953348. Epub 2021 Oct 19.
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Healthcare Providers' Vaccine Perceptions, Hesitancy, and Recommendation to Patients: A Systematic Review.医疗服务提供者对疫苗的认知、犹豫态度及向患者的推荐:一项系统评价
Vaccines (Basel). 2021 Jul 1;9(7):713. doi: 10.3390/vaccines9070713.