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佛山市南海区婴幼儿及儿童食物和吸入性过敏的患病率

Prevalence of food and inhalant allergies in infants and children from the Nanhai area of Foshan city.

作者信息

Yuan Xiao-Wen, Huang De Bing, Feng Guang-Rong, Ye Hui-Ling, Chen Ping, Yao Jie

机构信息

Department of Laboratory Medicine of the Sixth Affiliated Hospital, School of Medicine, South China University of Technology, No. 120 Gui Dan NanHai District, Foshan, Guangdong, 528200, China.

Department of Pediatrics of the Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, Guangdong, 528200, China.

出版信息

BMC Pediatr. 2025 Apr 28;25(1):334. doi: 10.1186/s12887-025-05664-y.

Abstract

BACKGROUND

The aim of our research was to explore the distribution characteristics of the most common food and inhalant allergens in children from Foshan city in Southwest China to provide evidence for the development of prevention and treatment strategies for allergic diseases in children.

METHODS

A total of 635 children who attended the Sixth Affiliated Hospital, South China University of Technology, were included in our retrospective study from February 2013 to October 2019. The sensitivity of immunoglobulin E (IgE) for 20 allergens (10 inhalant allergens and 10 food allergens) was determined. Statistical analysis was performed to analyze differences in the percentage of allergens among individuals according to sex, age and season.

RESULTS

Of the 635 patients, 200 tested positive for allergies. Dust mites were the most common inhalant allergens, followed by dog hair. The highest percentage of positive house dust mite sensitization was in the summer. Among the food allergens, individuals most frequently tested positive for wheat and milk allergies. The percentage of individuals with milk and egg allergies decreased with increasing age.

CONCLUSION

The most common allergens found in children from Foshan were dust mites, dog hair, wheat, tree nuts (hazelnut and pistachio), milk and peanuts. The results obtained could be helpful in determining the etiology of allergic diseases.

摘要

背景

我们研究的目的是探索中国西南部佛山市儿童中最常见的食物和吸入性过敏原的分布特征,为制定儿童过敏性疾病的防治策略提供依据。

方法

2013年2月至2019年10月,我们对在华南理工大学附属第六医院就诊的635名儿童进行了回顾性研究。测定了免疫球蛋白E(IgE)对20种过敏原(10种吸入性过敏原和10种食物过敏原)的敏感性。进行统计分析,以分析不同性别、年龄和季节个体之间过敏原阳性率的差异。

结果

在635例患者中,200例过敏检测呈阳性。尘螨是最常见的吸入性过敏原,其次是狗毛。屋尘螨致敏阳性率最高的季节是夏季。在食物过敏原中,个体对小麦和牛奶过敏检测呈阳性的频率最高。牛奶和鸡蛋过敏个体的比例随年龄增长而下降。

结论

佛山儿童中最常见的过敏原是尘螨、狗毛、小麦、坚果(榛子和开心果)、牛奶和花生。所得结果有助于确定过敏性疾病的病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d631/12036125/619fe863af91/12887_2025_5664_Fig1_HTML.jpg

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