Ultra-sparse view lung CT image reconstruction using generative adversarial networks and compressed sensing.

X-ray ionizing radiation from Computed Tomography (CT) scanning increases cancer risk for patients, thus making sparse view CT, which diminishes X-ray exposure by lowering the number of projections, highly significant in diagnostic imaging. However, reducing the number of projections inherently degrades image quality, negatively impacting clinical diagnosis. Consequently, attaining reconstructed images that meet diagnostic imaging criteria for sparse view CT is challenging. This paper presents a novel network (CSUF), specifically designed for ultra-sparse view lung CT image reconstruction. The CSUF network consists of three cohesive components including (1) a compressed sensing-based CT image reconstruction module (VdCS module), (2) a U-shaped end-to-end network, CT-RDNet, enhanced with a self-attention mechanism, acting as the generator in a Generative Adversarial Network (GAN) for CT image restoration and denoising, and (3) a feedback loop. The VdCS module enriches CT-RDNet with enhanced features, while CT-RDNet supplies the VdCS module with prior images infused with rich details and minimized artifacts, facilitated by the feedback loop. Engineering simulation experimental results demonstrate the robustness of the CSUF network and its potential to deliver lung CT images with diagnostic imaging quality even under ultra-sparse view conditions.