Le Guévelou Jennifer, Larnaudie Audrey, Blanchard Pierre, Pointreau Yoann, Castelli Joël
Laboratoire de traitement de l'image et du signal, University of Rennes, France.
Department of Research, Centre Eugène Marquis, Rennes, France.
Clin Transl Radiat Oncol. 2025 Apr 13;53:100962. doi: 10.1016/j.ctro.2025.100962. eCollection 2025 Jul.
In the past decades, several options have been designed in order to preserve vocal function in patients with early glottic cancer, such as transoral laser microsurgery, new surgical strategies such as partial laryngectomy and radiation therapy (RT). With the development of new radiation techniques enabling a more accurate delivery of radiation dose, and the possibility to deliver high dose per fraction while sparing adjacent organs-at-risks (OARs), stereotactic body radiotherapy (SBRT) is being increasingly tested in this disease setting. We aimed to shed light on this appealing strategy, as well as to underline both optimal target population and specific technical considerations.
在过去几十年里,为了保留早期声门癌患者的发声功能,已经设计了多种方案,如经口激光显微手术、部分喉切除术等新的手术策略以及放射治疗(RT)。随着能够更精确地给予放射剂量的新放射技术的发展,以及在 sparing adjacent organs-at-risks(OARs)的同时每次分割给予高剂量的可能性,立体定向体部放射治疗(SBRT)正在这种疾病背景下越来越多地得到测试。我们旨在阐明这种有吸引力的策略,并强调最佳目标人群和具体技术考量。