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一例未达可存活孕周的HELLP综合征典型病例报告

A typical presentation of previable HELLP syndrome: a case report.

作者信息

Ismerat Derar I I, Alsalameh Barah K S, Farash Raneen T M, Qnaibi Bayan, Mahfoud Amal, Jobran Afnan W M

机构信息

Gynecology and Obstetrics Specialist, AL Ahli Hospital, Hebron, West Bank P720, Palestine.

Gynecology and Obstetrics Assistant Professor, Hebron Medical University, Hebron, West Bank P720, Palestine.

出版信息

J Surg Case Rep. 2025 Apr 28;2025(4):rjaf255. doi: 10.1093/jscr/rjaf255. eCollection 2025 Apr.

DOI:10.1093/jscr/rjaf255
PMID:40297722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12035679/
Abstract

The rare condition known as HELLP syndrome is typified by hemolysis, low platelet counts, and high liver enzymes. We report a case of a 25-year-old primigravida who presented at a previable gestational age with nonspecific symptoms. She was diagnosed with hepatic infarction, a rare but severe complication of HELLP syndrome, and was managed promptly to prevent maternal morbidity and mortality.

摘要

罕见的HELLP综合征以溶血、血小板计数低和肝酶升高为典型特征。我们报告一例25岁初产妇的病例，她在未达可存活孕周时出现非特异性症状。她被诊断为肝梗死，这是HELLP综合征一种罕见但严重的并发症，并立即进行了治疗以预防孕产妇发病和死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0aed/12035679/05a7874e3775/rjaf255f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0aed/12035679/05a7874e3775/rjaf255f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0aed/12035679/05a7874e3775/rjaf255f1.jpg

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本文引用的文献

1
Rare but should never be forgotten: HELLP syndrome.罕见但绝不应被遗忘：HELLP综合征。
Case Rep Womens Health. 2024 Jan 23;41:e00584. doi: 10.1016/j.crwh.2024.e00584. eCollection 2024 Mar.
2
HELLP Syndrome and Differential Diagnosis with Other Thrombotic Microangiopathies in Pregnancy.妊娠合并HELLP综合征及其与其他血栓性微血管病的鉴别诊断
Diagnostics (Basel). 2024 Feb 6;14(4):352. doi: 10.3390/diagnostics14040352.
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Hypertensive complications of pregnancy: Hepatic consequences of preeclampsia through HELLP syndrome.
妊娠高血压并发症：通过HELLP综合征看子痫前期的肝脏后果。
Clin Liver Dis (Hoboken). 2023 Dec 8;22(6):195-199. doi: 10.1097/CLD.0000000000000088. eCollection 2023 Dec.
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Conservative Treatment of Huge Hepatic Subcapsular Hematoma Complicated with Hepatic Infarction after Cesarean Section Caused by HELLP Syndrome - a Case Report and Literature Review.HELLP 综合征致剖宫产术后巨大肝包膜下血肿合并肝梗死的保守治疗：1 例报告并文献复习。
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HELLP Syndrome-Holistic Insight into Pathophysiology.HELLP 综合征——对病理生理学的整体认识。
Medicina (Kaunas). 2022 Feb 21;58(2):326. doi: 10.3390/medicina58020326.
6
Thrombosis and thrombocytopenia in COVID-19 and after COVID-19 vaccination.COVID-19 相关血栓与血小板减少症，以及 COVID-19 疫苗接种后的血栓与血小板减少症。
Trends Cardiovasc Med. 2022 Jul;32(5):249-256. doi: 10.1016/j.tcm.2022.02.008. Epub 2022 Feb 22.
7
A case of massive hepatic infarction in severe preeclampsia as part of the HELLP syndrome.一例重度子痫前期并发HELLP综合征的大面积肝梗死病例。
Pan Afr Med J. 2020 Jun 9;36:78. doi: 10.11604/pamj.2020.36.78.23302. eCollection 2020.
8
Preeclampsia-induced Liver Dysfunction, HELLP syndrome, and acute fatty liver of pregnancy.子痫前期所致肝功能障碍、HELLP综合征及妊娠急性脂肪肝。
Clin Liver Dis (Hoboken). 2014 Sep 26;4(3):69-73. doi: 10.1002/cld.409. eCollection 2014 Sep.
9
Preeclampsia and HELLP syndrome, the role of the liver.子痫前期与HELLP综合征：肝脏的作用
J Matern Fetal Neonatal Med. 2021 Jan;34(1):117-123. doi: 10.1080/14767058.2019.1572737. Epub 2019 Jan 31.
10
Hepatic infarction induced by HELLP syndrome: a case report and review of the literature.HELLP 综合征导致肝梗死：病例报告及文献复习。
BMC Pregnancy Childbirth. 2018 May 30;18(1):191. doi: 10.1186/s12884-018-1799-9.