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成人感染性脊柱炎:诊断、管理及未来方向之旅

Infective Spondylitis in Adults: A Journey Through Diagnosis, Management, and Future Directions.

作者信息

Jung Woo-Seok, Choi Sung-Ryul, Kwon Ji-Won, Suk Kyung-Soo, Kim Hak-Sun, Moon Seong-Hwan, Park Si-Young, Shin Jae-Won, Lee Byung-Ho

机构信息

Department of Orthopedic Surgery, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul 07804, Republic of Korea.

Department of Orthopedic Surgery, College of Medicine, International St. Mary's Hospital, Catholic Kwandong University, Incheon 22711, Republic of Korea.

出版信息

Antibiotics (Basel). 2025 Apr 9;14(4):391. doi: 10.3390/antibiotics14040391.

Abstract

Infective spondylitis is a rare but potentially devastating spinal infection that requires timely diagnosis and appropriate treatment to prevent severe complications, including neurological deficits and spinal deformity. Despite advancements in diagnostic imaging, microbiological techniques, and antimicrobial therapies, clinical challenges persist because of the disease's insidious onset, varied etiologies, and increasing antimicrobial resistance. This review article provides a comprehensive analysis of the current literature on the epidemiology, pathophysiology, diagnostic approaches, and treatment strategies for infective spondylitis.

摘要

感染性脊柱炎是一种罕见但可能具有毁灭性的脊柱感染,需要及时诊断和适当治疗以预防严重并发症,包括神经功能缺损和脊柱畸形。尽管在诊断成像、微生物学技术和抗菌治疗方面取得了进展,但由于该疾病起病隐匿、病因多样且抗菌耐药性不断增加,临床挑战依然存在。本文综述对目前关于感染性脊柱炎的流行病学、病理生理学、诊断方法和治疗策略的文献进行了全面分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12024046/5edf7268c502/antibiotics-14-00391-g001.jpg

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