Misiewicz Aleksander, Badura Krzysztof, Matuszewska-Brycht Oliwia, Krekora Jan, Drożdż Jarosław
2nd Department of Cardiology, Medical University of Lodz, 92-213 Lodz, Poland.
Biomedicines. 2025 Mar 21;13(4):769. doi: 10.3390/biomedicines13040769.
Acute coronary syndromes (ACS) are a leading cause of death and impairment in the adult population. Precise identification and modification of risk factors is crucial for a favorable clinical outcome. In this review, we aim to provide a comprehensive overview of the significance of iron deficiency (ID) in patients with ACS, particularly myocardial infarction (MI). The paper evaluates the impact of ID on the prognosis of ACS patients, highlighting its potential influence on myocardial healing, regeneration and cardiovascular events during the follow-up period. The findings suggest that iron deficiency may have a negative impact on the prognosis of patients with MI, resulting in worse quality of life, physical capacity and higher rehospitalization rates in comparison to patients with normal iron status. Iron supplementation in patients with MI could be beneficial and may have an effect on myocardial healing and left ventricular remodeling.
急性冠状动脉综合征（ACS）是成年人群死亡和功能障碍的主要原因。精确识别和改变危险因素对于获得良好的临床结果至关重要。在本综述中，我们旨在全面概述缺铁（ID）在ACS患者，特别是心肌梗死（MI）患者中的重要性。本文评估了缺铁对ACS患者预后的影响，强调了其在随访期间对心肌愈合、再生和心血管事件的潜在影响。研究结果表明，缺铁可能对MI患者的预后产生负面影响，与铁状态正常的患者相比，会导致生活质量、身体能力更差，再住院率更高。对MI患者补充铁剂可能有益，并且可能对心肌愈合和左心室重构产生影响。
