Behrendt W, Kalff J, Giani G, Minale C, Barsnick F
Infusionsther Klin Ernahr. 1985 Jun;12(3):153-60.
A new system for continuous measurement of oxygen uptake was tested (EMC). Delivered tidal volumes of the system, the accuracy of the oxygen sensor cell, measurement of the oxygen uptake related to different inspiratory oxygen concentrations as well as comparative tests of oxygen uptake according to Fick's principle were studied. Furthermore, we looked for possible leakages in the system. Following to our results even thorough maintenance could not entirely prevent leakages. There was a remarkable increase in measured oxygen uptake if inspiratory oxygen concentration was increased. While carbon-dioxide output was measured at constant levels this led to low respiratory quotients, some of these were less than 0.5. This was caused by a construction error of the system which could be corrected in the meantime. In 70 comparative tests of oxygen uptake between EMC and Fick's principle (measurement of cardiac output and arteriovenous oxygen content difference) we found a mean difference of about 10% (p less than or equal to 0.001) with nearly identical standard deviations. The EMC measured the higher oxygen uptake. Based on our experience the EMC is suitable for continuous measurement of oxygen uptake but it needs good knowledge of the system and the underlying measuring procedures. Additional technical improvements seem to be possible.
对一种用于连续测量氧摄取量的新系统(EMC)进行了测试。研究了该系统的潮气量输送、氧传感器单元的准确性、与不同吸气氧浓度相关的氧摄取量测量以及根据菲克原理进行的氧摄取量对比测试。此外,我们还查找了系统中可能存在的泄漏情况。根据我们的结果,即使进行彻底维护也无法完全防止泄漏。如果吸气氧浓度增加,测得的氧摄取量会显著增加。在二氧化碳输出量保持恒定水平进行测量时,这导致呼吸商较低,其中一些低于0.5。这是由系统的一个结构错误导致的,目前该错误已可纠正。在对EMC和菲克原理(测量心输出量和动静脉氧含量差)之间的氧摄取量进行的70次对比测试中,我们发现平均差异约为10%(p小于或等于0.001),标准差几乎相同。EMC测得的氧摄取量更高。根据我们的经验,EMC适用于连续测量氧摄取量,但需要对该系统及其基础测量程序有充分了解。似乎还可以进行进一步的技术改进。