Hao Yanli, Liu Xiajing, Wu Tingting, Liang Qiuni
Department of Ultrasound, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Department of Radiology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Front Med (Lausanne). 2025 Apr 15;12:1537986. doi: 10.3389/fmed.2025.1537986. eCollection 2025.
Endosalpingiosis, a rare benign condition characterized by ectopic fallopian tube-like epithelium, often coexists with endometriosis. This case report presents a unique instance of florid cystic endosalpingiosis confined to the uterine myometrium-marking the first documented case without associated pelvic pathology. Using multimodal imaging and histopathological analysis, we highlight key diagnostic approaches to distinguish this condition from malignant mimics.
A 47-year-old woman with a 2-year history of chronic pelvic pain and recent irregular bleeding underwent surgical exploration after imaging revealed isolated, non-communicating cystic lesions within the myometrium. Histopathological examination identified cyst walls lined with ciliated pseudostratified epithelium, confirmed as benign through immunohistochemistry. A 6-year follow-up showed no evidence of recurrence.
Florid cystic endosalpingiosis should be considered in the differential diagnosis of cystic uterine lesions. Establishing standardized imaging criteria and adopting fertility-preserving management strategies can help avoid unnecessary radical interventions, optimizing outcomes for premenopausal women.
输卵管内膜异位症是一种罕见的良性疾病，其特征为异位的输卵管样上皮，常与子宫内膜异位症并存。本病例报告呈现了一例罕见的、局限于子宫肌层的囊性输卵管内膜异位症——这是首例无相关盆腔病变记录的病例。通过多模态成像和组织病理学分析，我们重点介绍了将该疾病与恶性病变鉴别开来的关键诊断方法。
一名47岁女性，有2年慢性盆腔疼痛病史且近期出现不规则出血，影像学检查发现子宫肌层内有孤立的、不连通的囊性病变后，接受了手术探查。组织病理学检查发现囊肿壁内衬有纤毛假复层上皮，免疫组化证实为良性。6年随访显示无复发迹象。
在子宫囊性病变的鉴别诊断中应考虑到典型的囊性输卵管内膜异位症。建立标准化的成像标准并采用保留生育功能的管理策略有助于避免不必要的根治性干预，为绝经前女性优化治疗结果。
