青年起病2型糖尿病大血管和微血管并发症的剖析：一项范围综述
Profiling of Macrovascular and Microvascular Complications in Young-Onset Type 2 Diabetes: A Scoping Review.
作者信息
Harihar Anupama, Maiya G Arun, Shetty Sahana, K N Shivashankar, Bhat Shyamasunder, Kumar Sachin, Jadhav Radhika Aditya
机构信息
Centre for Podiatry & Diabetic Foot Care and Research, Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Department of Endocrinology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
出版信息
Clin Diabetes. 2024 Nov 14;43(2):253-261. doi: 10.2337/cd24-0063. eCollection 2025 Spring.
Abstract
Young-onset type 2 diabetes is defined as type 2 diabetes diagnosed before the age of 40 years. It is characterized by more aggressive pathology compared with type 2 diabetes diagnosed later in life, leading to earlier susceptibility to macrovascular and microvascular complications. This scoping review comprehensively profiles the complications associated with young-onset type 2 diabetes. Early detection of these complications, comprehensive risk assessment, and multifaceted glycemic management will improve quality of life and overall life expectancy in this population.
摘要
青年发病型2型糖尿病定义为40岁之前诊断出的2型糖尿病。与成年后期诊断出的2型糖尿病相比，其病理表现更为侵袭性，导致更早出现大血管和微血管并发症易感性。本范围综述全面概述了与青年发病型2型糖尿病相关的并发症。早期发现这些并发症、进行全面风险评估以及多方面的血糖管理将改善该人群的生活质量和总体预期寿命。
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Profiling of Macrovascular and Microvascular Complications in Young-Onset Type 2 Diabetes: A Scoping Review.青年起病2型糖尿病大血管和微血管并发症的剖析：一项范围综述
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本文引用的文献
1
Diabetes complications and cognitive function in young adults with youth-onset type 1 or type 2 diabetes: the SEARCH for Diabetes in Youth Study.青年起病 1 型或 2 型糖尿病患者的糖尿病并发症与认知功能：青少年糖尿病研究（SEARCH）。
Pediatr Diabetes. 2023;2023. doi: 10.1155/2023/4860831. Epub 2023 Apr 8.
2
Ethnic differences in the association between age at diagnosis of diabetes and the risk of cardiovascular complications: a population-based cohort study.种族差异与糖尿病诊断年龄和心血管并发症风险的关联：基于人群的队列研究。
Cardiovasc Diabetol. 2023 Sep 4;22(1):241. doi: 10.1186/s12933-023-01951-z.
3
Diabetes knowledge, self-efficacy and dietary, psychological and physical health barriers: Comparing young and usual-onset type 2 diabetes.糖尿病知识、自我效能以及饮食、心理和身体健康障碍：比较青年型和成年型2型糖尿病
Diabet Med. 2024 Mar;41(3):e15207. doi: 10.1111/dme.15207. Epub 2023 Aug 28.
4
Prevalence and risk of diabetic complications in young-onset versus late-onset type 2 diabetes mellitus.早发性与晚发性 2 型糖尿病患者的糖尿病并发症患病率和风险。
Diabetes Metab. 2022 Nov;48(6):101389. doi: 10.1016/j.diabet.2022.101389. Epub 2022 Sep 19.
5
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