Johnson Abigail S, Chapman Teresa, Tao Ting Y, Fowler Amy M
University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
J Breast Imaging. 2025 Sep 2;7(4):492-506. doi: 10.1093/jbi/wbaf006.
The clinical approach, differential diagnosis, diagnostic imaging, and management of breast masses differs between adult and pediatric patients. Breast symptoms in pediatric populations are likely to be normal, variants of normal development, or classically benign. When evaluating pediatric patients, a thorough history and physical examination is key and may include US imaging if clinically indicated. Currently, there are no consensus guidelines from professional societies specific to the imaging evaluation, reporting, or management of the pediatric breast. Inappropriate utilization of additional imaging or biopsy recommendations can cause stress to patients and caregivers, added financial costs, and potential damage to the developing breast. As such, it is increasingly important for radiologists to have a clear understanding of the expected physical and imaging findings for developing breast tissue, developmental abnormalities, benign conditions, and rare malignancies. This review summarizes the expected normal developmental breast changes in the pediatric population as well as common anatomic variants. Both benign and rare malignant breast pathologies are reviewed with a discussion about clinical presentation and management to guide breast imaging trainees and practicing radiologists.
成人和儿童患者乳腺肿块的临床处理、鉴别诊断、诊断性影像学检查及治疗方法有所不同。儿科人群的乳腺症状可能是正常的、正常发育的变异情况,或典型的良性症状。评估儿科患者时,全面的病史和体格检查是关键,如有临床指征,可能还包括超声成像检查。目前,专业学会尚无针对儿科乳腺影像学评估、报告或治疗的共识性指南。不恰当的额外影像学检查或活检建议的使用会给患者及其照料者带来压力,增加经济成本,并可能对发育中的乳腺造成损害。因此,放射科医生清楚了解发育中乳腺组织的预期体格检查和影像学表现、发育异常、良性疾病及罕见恶性肿瘤情况变得越来越重要。本综述总结了儿科人群中预期的正常乳腺发育变化以及常见的解剖变异。本文对良性和罕见的恶性乳腺病变进行了综述,并讨论了临床表现及治疗方法,以指导乳腺影像专业学员和执业放射科医生。