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自体肌瓣转移或肌皮瓣移植治疗术后慢性脓胸合并支气管胸膜瘘的疗效评估

Efficacy evaluation of autologous muscle flap transposition or myocutaneous flap transplantation for postoperative chronic empyema with bronchopleural fistula.

作者信息

Wang Lei, Lv Yunjie, Zhao Guoxue, Li Guangjian, He Zhongliang, Huang Yunchao, Zhao Guangqiang

机构信息

Department of Thoracic Surgery, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital/Peking University Cancer Hospital Yunnan, Kunming, Yunnan, China.

Department of Cardiothoracic Surgery, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.

出版信息

Ann Med. 2025 Dec;57(1):2499953. doi: 10.1080/07853890.2025.2499953. Epub 2025 Apr 30.

Abstract

BACKGROUND

Chronic empyema with bronchopleural fistula (BPF) after pulmonary resection is difficult to treat. The aim of the study is to explore the efficacy of autologous muscle flap or myocutaneous flap on chronic empyema with BPF.

METHODS

Retrospective analysis of 10 patients with postoperative chronic empyema with BPF treated in our hospital, including 8 males and 2 females, with ages ranging from 20 to 83 years, yielding an average age of (51.00 ± 19.22) years. The treatment of all patients with chronic empyema follows a staged surgical model. The first stage of surgery involves debridement, partial rib resection, and fistula closure, while the second stage includes autologous muscle flap transposition or free myocutaneous flap transplantation to eliminate the abscess cavity. The primary objectives of the first-stage surgery include ensuring adequate drainage, controlling infection, and achieving fistula closure. In contrast, the key focus of the second-stage surgery is the complete filling of the abscess cavity with a sufficient volume of autologous tissue flap.

RESULTS

There were no perioperative deaths. The average follow-up was (19.88 ± 9.03) months. None of the 10 patients had recurrence of empyema and BPF. All autologous muscle flaps or myocutaneous flaps survived. Postoperative chest computed tomography (CT) or magnetic resonance imaging (MRI) showed that the abscess cavity disappeared.

CONCLUSIONS

The application of autologous muscle flap or myocutaneous flap represents an effective approach for the treatment of chronic empyema with BPF, demonstrating satisfactory clinical outcomes in the short to medium term.

摘要

背景

肺切除术后合并支气管胸膜瘘(BPF)的慢性脓胸难以治疗。本研究旨在探讨自体肌瓣或肌皮瓣治疗合并BPF的慢性脓胸的疗效。

方法

回顾性分析我院收治的10例术后慢性脓胸合并BPF患者,其中男性8例,女性2例,年龄20~83岁,平均年龄(51.00±19.22)岁。所有慢性脓胸患者均采用分期手术模式治疗。第一阶段手术包括清创、部分肋骨切除和瘘管闭合,而第二阶段包括自体肌瓣转移或游离肌皮瓣移植以消除脓肿腔。第一阶段手术的主要目标包括确保充分引流、控制感染和实现瘘管闭合。相比之下,第二阶段手术的关键重点是用足够体积的自体组织瓣完全填充脓肿腔。

结果

围手术期无死亡病例。平均随访时间为(19.88±9.03)个月。10例患者均无脓胸和BPF复发。所有自体肌瓣或肌皮瓣均存活。术后胸部计算机断层扫描(CT)或磁共振成像(MRI)显示脓肿腔消失。

结论

自体肌瓣或肌皮瓣的应用是治疗合并BPF的慢性脓胸的有效方法,在短期至中期显示出令人满意的临床效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d765/12044905/96614226a5e3/IANN_A_2499953_F0001_C.jpg

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