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手术联合支气管镜治疗真菌性脓胸:5 例报告。

Surgical operation combined with bronchoscopy in the treatment of fungal empyema: 5 cases report.

机构信息

Department of Cardiothoracic Surgery, Hangzhou, Zhejiang Province, China.

Department of Cardiothoracic Surgical Nursing, Hangzhou, Zhejiang Province, China.

出版信息

Medicine (Baltimore). 2022 Oct 21;101(42):e31080. doi: 10.1097/MD.0000000000031080.

Abstract

RATIONALE

Fungal empyema is a chronic refractory disease. It is difficult to control thoracic infection, and it is faced with the problem of recurrence. How to control the infection and reduce the probability of recurrence is a difficult problem. Surgical operation combined with endobronchial therapy was used to control infection, seal the fistula and eliminate residual cavity and achieved good results.

PATIENT CONCERNS

A total of 5 patients with fungal empyema were treated from 2019 to 2021, aged 27 to 72 years, with an average age of 54.8 ± 7.6 years. Two cases were on the left side and 3 cases on the right side.

DIAGNOSIS

While meeting the diagnostic criteria of empyema, the diagnosis of fungus in pus culture or the discovery of fungus in deep tissue pathology confirmed the diagnosis of fungal empyema in the 5 cases.

INTERVENTIONS

Through surgical operations combined with bronchoscopy and individualized treatment, the infection was controlled, the fistulas were blocked, and the pus cavity was filled.

OUTCOMES

After 11 to 30 months of follow-up, the muscle flap in the abscess cavity was mildly atrophied, and there was no recurrence of empyema. Three patients who completed the second-stage operation had their chest tubes removed and returned to normal life. The 2 patients who did not complete the second-stage operation had no recurrence of thoracic infection and no recurrence of cough or fever, and their quality of life was greatly improved.

LESSONS

Surgical operation combined with bronchoscopy is a reliable method for the treatment of fungal empyema, which can find and plug the fistula more efficiently and eliminate the residual cavity by surgery to avoid recurrence. Therefore, it is a recommended treatment method.

摘要

背景

真菌性脓胸是一种慢性难治性疾病,难以控制胸内感染,且面临复发问题,如何控制感染、减少复发概率是一个难题。采用手术联合支气管镜内治疗的方法控制感染、封堵瘘口、消除残腔,取得了较好的效果。

患者情况

2019 年至 2021 年共收治真菌性脓胸患者 5 例,年龄 27~72 岁,平均 54.8±7.6 岁;左侧 2 例,右侧 3 例。

诊断

5 例均符合脓胸的诊断标准,同时脓液培养真菌阳性或深部组织病理发现真菌,确诊为真菌性脓胸。

干预

通过手术联合支气管镜,并根据个体情况进行治疗,控制感染、封堵瘘口、填充脓腔。

结果

5 例患者随访 11~30 个月,脓肿腔内肌瓣轻度萎缩,无脓胸复发。完成二期手术的 3 例患者拔除胸腔引流管,恢复正常生活。未完成二期手术的 2 例患者,胸内感染未复发,无咳嗽、发热,生活质量明显提高。

结论

手术联合支气管镜治疗真菌性脓胸是一种可靠的方法,能更高效地找到并封堵瘘口,同时通过手术消除残腔,避免复发,是一种推荐的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3e7/9592517/84473dbd495f/medi-101-e31080-g001.jpg

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