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鼓室成形术联合咽鼓管成形术与单纯鼓室成形术的疗效比较:一项系统评价与Meta分析

Outcomes of combined tympanoplasty and eustachian tuboplasty versus tympanoplasty alone: A systematic review and meta-analysis.

作者信息

Al-Hamoud Mohammed A, AlShehri Mona A, Al-Marir Azza M, Alshahrani Aishah S, Assiri Majed, ALGhamdi Fares E

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Ahad Rufaidah General Hospital, Aseer Health Cluster, Abha, Saudi Arabia.

Department of Otorhinolaryngology-Head and Neck Surgery, Aseer Central Hospital, Aseer Health Cluster, Abha, Saudi Arabia.

出版信息

Eur Arch Otorhinolaryngol. 2025 Apr 30. doi: 10.1007/s00405-025-09411-y.

Abstract

PURPOSE

Eustachian tube dysfunction plays a crucial role in the pathophysiology of chronic otitis media and impacts surgical outcomes of tympanoplasty. We aimed to assess the outcomes of combined tympanoplasty with eustachian tuboplasty compared to tympanoplasty alone with respect totes graft success rate, hearing outcome, tympanometry measures, and improvement of eustachian tube function.

METHODS

This review has been registered in the Prospective Register of Systematic Reviews. (CRD42024614970) and was conducted according to the PRISMA guidelines. Four major databases-PubMed, ScienceDirect, Web of Science, and Google Scholar-were used for the electronic search to identify relevant studies.

RESULTS

Seven studies involving 386 patients were included; 195 (50.5%) and 191 patients (49.5%) were assigned to the tympanoplasty plus eustachian tuboplasty and tympanoplasty alone groups, respectively. The meta-analysis revealed significant improvements in graft success rates (Odds Ratio = 1.90, 95% CI: 1.02 to 3.54, p = 0.042), air-bone gap (MD = -2.07, 95% CI: -3.78 to -0.36, p = 0.018), and eustachian tube scores (Mean difference = 2.00, 95% CI: 0.02 to 3.98, p = 0.048) in the combined group compared to in the control group. Only minor complications were observed in some studies, such as mild tympanic membrane retraction, graft myringitis, and temporary patulous eustachian tubes.

CONCLUSION

Combining tuboplasty with tympanoplasty is an effective procedure with significant improvements in graft success rates, hearing outcomes, and eustachian tube function scores. Eustachian tuboplasty is a safe and successful procedure with very few potential complications.

摘要

目的

咽鼓管功能障碍在慢性中耳炎的病理生理学中起关键作用,并影响鼓室成形术的手术效果。我们旨在评估联合鼓室成形术与咽鼓管成形术相比单纯鼓室成形术在移植物成功率、听力结果、鼓室导抗测量以及咽鼓管功能改善方面的效果。

方法

本综述已在系统评价前瞻性注册库中注册(CRD42024614970),并按照PRISMA指南进行。使用四个主要数据库——PubMed、ScienceDirect、科学网和谷歌学术进行电子检索,以识别相关研究。

结果

纳入了7项涉及386例患者的研究;分别有195例(50.5%)和191例患者(49.5%)被分配到鼓室成形术加咽鼓管成形术组和单纯鼓室成形术组。荟萃分析显示,与对照组相比,联合组的移植物成功率(优势比=1.90,95%可信区间:1.02至3.54,p=0.042)、气骨导差(MD=-2.07,95%可信区间:-3.78至-0.36,p=0.018)和咽鼓管评分(平均差=2.00,95%可信区间:0.02至3.98,p=0.048)有显著改善。在一些研究中仅观察到轻微并发症,如轻度鼓膜内陷、移植物鼓膜炎和暂时性咽鼓管异常开放。

结论

咽鼓管成形术与鼓室成形术相结合是一种有效的手术方法,在移植物成功率、听力结果和咽鼓管功能评分方面有显著改善。咽鼓管成形术是一种安全且成功的手术,潜在并发症极少。

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