Prednisone effect on microvascular permeability in patients with inflammatory rheumatic diseases.
作者信息
Manthorpe R, Hansen T M, Junker P, Lorenzen I, Utne H E
出版信息
Scand J Rheumatol. 1979;8(3):139-41. doi: 10.3109/03009747909114445.
PMID:40306
Abstract
The transcapillary escape rate of albumin was measured in 27 consecutive patients with inflammatory rheumatic diseases before and after 1 and 7 days of prednisone treatment in doses of 45 mg/day. The transcapillary escape rate decreased from 7.33%/h (range 5.11-9.55) before prednisone treatment to 3.11%/h (0.04-6.18) (p less than 0.05) after 1 day of treatment and 5.80%/h (4.36-7.24) after 7 days of treatment. It is concluded that prednisone inhibits vascular permeability in patients with inflammatory rheumatic diseases.
摘要
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