Olson L E, Wilson T A, Rodarte J R
J Appl Physiol (1985). 1985 Aug;59(2):521-7. doi: 10.1152/jappl.1985.59.2.521.
The conically shaped caudal lobes of dog lungs were submerged, tip downward in saline, and the lateral surfaces of the lobes were thereby exposed to a hydrostatic gradient in transpulmonary pressure. The force that was required to balance the buoyancy was applied through a clip attached to the tip of the lobe. The locations of metal markers implanted in the parenchyma and attached to the surface were tracked, and regional volume and the horizontal and vertical components of strain were obtained as functions of vertical position. An engineering analysis of the deformation is qualitatively consistent with the data, but the predicted strains are larger than the observed strains. From the experimental and analytical results, we conclude that, for this deformation, the regional volume-local transpulmonary pressure curve closely follows the pressure-volume curve because negative horizontal strains nearly balance the positive vertical strain caused by the buoyancy force.
将犬肺呈圆锥形的尾叶尖端向下浸入盐水中，从而使叶的侧面暴露于跨肺压的流体静力梯度中。通过连接到叶尖端的夹子施加平衡浮力所需的力。追踪植入实质并附着于表面的金属标记的位置，并获得区域体积以及应变的水平和垂直分量作为垂直位置的函数。对变形的工程分析在定性上与数据一致，但预测的应变大于观察到的应变。从实验和分析结果中，我们得出结论，对于这种变形，区域体积 - 局部跨肺压曲线紧密跟随压力 - 体积曲线，因为负水平应变几乎平衡了由浮力引起的正垂直应变。
