Han Lin, Wang Zijing, Zhang Junbo, Duan Maoli, Diao Tongxiang, Yu Lisheng
Department of Otolaryngology, Head and Neck Surgery, People's Hospital, Peking University, Beijing, China.
Department of Otorhinolaryngology, Beijing Jishuitan Hospital, Fourth Clinical Medical College of Peking University, Beijing, China.
Acta Otolaryngol. 2025 Jul;145(7):607-612. doi: 10.1080/00016489.2025.2491651. Epub 2025 Apr 30.
The correlation of Meniere's disease (MD) and migraine remains unclear.
To explore the relation of MD and migraine by analyzing the postoperative relief of vertigo and migraine in MD patients with migraine.
104 MD patients were enrolled. The monthly vertigo episodes (MVE) and migraine headache index (MHI) were used for assessing effectiveness at pre- and post-endolymphatic sac decompression (ELSD). First, patients were divided into MD with migraine and MD two groups with vertigo relief rates compared. Then, the postoperative relief of vertigo and migraine in MD patients with migraine was analyzed.
The postoperative vertigo relief rates for MD and MD with migraine groups were 46.7% and 40.68% with no significant difference. In MD patients with migraine, postoperative MVE and MHI decreased significantly. The Kappa value calculated for vertigo and migraine outcomes was 0.505. The absence of hypertension was independently predictive of relief of vertigo and migraine. The male was independently predictive for relief of migraine.
ELSD is effective for MD patients with migraine. The postoperative relief of vertigo and migraine has a certain consistency, suggesting MD and migraine may share some common pathogenesis which may be related to inflammation.
梅尼埃病（MD）与偏头痛之间的相关性仍不明确。
通过分析偏头痛型梅尼埃病患者眩晕和偏头痛的术后缓解情况，探讨梅尼埃病与偏头痛的关系。
纳入104例梅尼埃病患者。采用每月眩晕发作次数（MVE）和偏头痛头痛指数（MHI）评估内淋巴囊减压术（ELSD）前后的疗效。首先，将患者分为偏头痛型梅尼埃病组和梅尼埃病组，比较两组眩晕缓解率。然后，分析偏头痛型梅尼埃病患者眩晕和偏头痛的术后缓解情况。
梅尼埃病组和偏头痛型梅尼埃病组术后眩晕缓解率分别为46.7%和40.68%，差异无统计学意义。在偏头痛型梅尼埃病患者中，术后MVE和MHI显著降低。眩晕和偏头痛结局的Kappa值为0.505。无高血压是眩晕和偏头痛缓解的独立预测因素。男性是偏头痛缓解的独立预测因素。
内淋巴囊减压术对偏头痛型梅尼埃病患者有效。眩晕和偏头痛的术后缓解具有一定的一致性，提示梅尼埃病和偏头痛可能具有一些共同的发病机制，可能与炎症有关。
