Abu Bonsra Emmanuel, Osei Petra Amankwah, Kyere Gideon Amankwah, Adam Stephen
Department of Population and Behavioural Sciences, Fred N. Binka School of Public Health, University of Health and Allied Sciences, Hohoe, Ghana.
Family and Community Health, Fred N. Binka School of Public Health, University of Health and Allied Sciences, Hohoe, Ghana.
BMC Public Health. 2025 Apr 30;25(1):1595. doi: 10.1186/s12889-025-22810-4.
Globally, malaria remains a critical public health challenge, particularly in sub-Saharan Africa. Pregnant mothers are at a relatively higher risk of severe malaria than their non-pregnant counterparts due to natural immune suppression. In Ghana, the prevalence of malaria during pregnancy poses significant risks to maternal and fetal health. The primary aim of this study was to determine the factors associated with malaria in pregnancy among women attending ANC clinics in the Kwadaso Municipal, Ghana.
This study employed a cross-sectional design to gather quantitative data from 405 pregnant women using a multistage sampling method. Data were collected through structured questionnaires administered. Descriptive and inferential statistics, including frequency tables, percentages, and regression analysis using Stata 17, were utilized for data analysis.
Out of the 405 participants, 201 (49.6%) tested positive for malaria, while the knowledge level of malaria among pregnant women was 16.5%. Bivariate logistic regression was conducted to determine the factors influencing malaria among pregnant women. The results showed that pregnant women aged 17 to 25 years are 5.41 times more likely to have high malaria prevalence compared to 40 to 51 age group (cOR = 5.41, 95% CI [2.20-6.83], p = 0.015). Pregnant women who do not use insecticide-treated bed nets regularly users are 10.3 times more likely to have high malaria compared to users (cOR = 10.3, 95% CI [4.05-11.02], p < 0.001). Multivarite logistic regression also showed that Women earning between 100 to 500 cedis are 7.0 times more likely to have malaria compared to those earning 3000 cedis or more (aOR = 7.0, 95% CI [3.23-8.74], p = 0.003). Women who do not regularly use insecticide-treated bed nets are 15.0 times more likely to experience high malaria prevalence compared to those who do use them (aOR = 15.0, 95% CI [7.03-16.09], p < 0.001), Lack of mosquito nets significantly increases the likelihood of 9.53 times high malaria prevalence (aOR = 9.53, 95% CI [4.07-10.95], p = 0.003). Pregnant women with Junior High School (JHS) education are 3.50 times more likely to have high malaria compared to those with no formal education (aOR = 3.50, 95% CI [1.32-4.78], p = 0.002).
This study highlights the significant burden of malaria among pregnant women in Kwadaso Municipal. Factors such as age, education levels, and socioeconomic status were identified as key determinants of malaria diagnosis. Additionally, environmental and preventive factors, including insufficient use of insecticide-treated bed nets and proximity to stagnant water, contributed to the likelihood of malaria. The study suggests that the Ghana Health Service and Ministry of Health should improve access to insecticide-treated bed nets, enhance malaria awareness, and integrate regular malaria screening into antenatal care.
在全球范围内,疟疾仍然是一项严峻的公共卫生挑战,尤其是在撒哈拉以南非洲地区。由于自然免疫抑制,孕妇感染重症疟疾的风险相对高于非孕妇。在加纳,孕期疟疾的流行对孕产妇和胎儿健康构成重大风险。本研究的主要目的是确定加纳夸达索市参加产前保健诊所的孕妇中与孕期疟疾相关的因素。
本研究采用横断面设计,通过多阶段抽样方法从405名孕妇中收集定量数据。数据通过结构化问卷收集。数据分析采用描述性和推断性统计方法,包括频率表、百分比以及使用Stata 17进行回归分析。
在405名参与者中,201人(49.6%)疟疾检测呈阳性,而孕妇对疟疾的知晓率为16.5%。进行二元逻辑回归以确定影响孕妇疟疾感染的因素。结果显示,17至25岁的孕妇患疟疾的可能性是40至51岁年龄组的5.41倍(校正比值比[cOR]=5.41,95%置信区间[CI][2.20 - 6.83],p = 0.015)。不经常使用经杀虫剂处理蚊帐的孕妇感染疟疾的可能性是经常使用者的10.3倍(cOR = 10.3,95% CI[4.05 - 11.02],p < 0.001)。多变量逻辑回归还显示,收入在100至500塞地之间的女性患疟疾的可能性是收入3000塞地或以上女性的7.0倍(调整后比值比[aOR]=7.0,95% CI[3.23 - 8.74],p = 0.003)。不经常使用经杀虫剂处理蚊帐的女性患疟疾的可能性是经常使用者的15.0倍(aOR = 15.0,95% CI[7.03 - 16.09],p < 0.001),缺乏蚊帐会使患疟疾的可能性显著增加9.53倍(aOR = 9.53,95% CI[4.07 - 10.95],p = 0.003)。接受初中教育的孕妇患疟疾的可能性是未接受正规教育孕妇的3.50倍(aOR = 3.50,95% CI[1.32 - 4.78],p = 0.002)。
本研究凸显了夸达索市孕妇中疟疾的重大负担。年龄、教育水平和社会经济地位等因素被确定为疟疾诊断的关键决定因素。此外,环境和预防因素,包括经杀虫剂处理蚊帐使用不足以及靠近积水区域,也增加了患疟疾的可能性。该研究表明,加纳卫生服务局和卫生部应改善经杀虫剂处理蚊帐的获取,提高疟疾意识,并将定期疟疾筛查纳入产前保健。