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主动脉瓣切开术治疗先天性主动脉瓣狭窄。

Aortic valvotomy in the treatment of congenital aortic stenosis.

作者信息

Mackworth-Young C G, Dawkins K D, Kay P H, Paneth M

出版信息

J Cardiovasc Surg (Torino). 1985 Sep-Oct;26(5):433-8.

PMID:4030874
Abstract

Forty patients aged 1.5-23 (mean 11) years underwent open aortic valvotomy for congenital aortic stenosis. Mean preoperative peak aortic gradient for the group was 88 (SD +/- 24) mmHg. Follow-up data was available on all patients for a total of 269 patient-years (means 6.6 year). There was no early mortality, and only one (2.5%) late death. During the follow-up period 3 patients (7.5%) required aortic valve replacement. Actuarial survival curves predict a 7 year survival of 95.7 (SE +/- 8.4%) for all patients, and a freedom from reoperation rate at 6 years of 8.7 (SE +/- 9.3)%. Symptomatic results in the survivors were excellent (97.5% NYHA Class I). Data from this series compares favourably with the literature which is reviewed for a total of 1136 patients undergoing open aortic valvotomy.

摘要

40例年龄在1.5至23岁(平均11岁)的患者因先天性主动脉瓣狭窄接受了开放性主动脉瓣切开术。该组患者术前平均主动脉峰值梯度为88(标准差±24)mmHg。所有患者均有总计269患者年(平均6.6年)的随访数据。无早期死亡,仅1例(2.5%)晚期死亡。随访期间,3例患者(7.5%)需要进行主动脉瓣置换。精算生存曲线预测所有患者7年生存率为95.7(标准误±8.4%),6年再次手术率为8.7(标准误±9.3)%。幸存者的症状改善情况良好(97.5%为纽约心脏协会I级)。本系列数据与对1136例接受开放性主动脉瓣切开术患者的文献综述相比具有优势。

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