Kujovic Milenko, Benz Daniel, Baumann Bruno, Engelke Christina, Margittai Zsofia, Christl Julia, Seitz Rüdiger J, Menge Til, Bahr Christian, Riesbeck Mathias, Meisenzahl Eva, Schmidt-Kraepelin Christian
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Centre for Neurology and Neuropsychiatry, LVR-Klinikum Düsseldorf, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Neuropsychiatr Dis Treat. 2025 Apr 26;21:955-964. doi: 10.2147/NDT.S503053. eCollection 2025.
Although neurological patients are known to suffer from psychiatric comorbidities, appropriate, cost-effective, standardized screening measures are still scarce in clinical practice. We examined a multidimensional psychiatric screening for neurological patients.
We report a retrospective analysis of multidimensional psychiatric screening using the HADS-D and the BSI-53 in 437 consecutive neurological inpatients. The HADS-D describes depressive and anxiety symptoms, while the BSI-53 expands the symptom clusters associated with psychiatric disorders by somatization, obsessive-compulsion, interpersonal sensitivity, hostility, paranoid ideation, psychoticism and global measures of mental distress. Patients were separated in diagnostic groups (vascular, demyelinating, degenerative, epileptic, other) with regard to their diagnosis.
Our results corroborate previous findings of high prevalence of psychiatric symptoms particularly in younger patients (< 60 years). Furthermore, 27.2% were above the HADS-D cut-off for anxiety and 25.4% for depression. We found no differences between diagnostic groups. Importantly, we also show that neurological patients suffer from mental distress beyond anxiety and depression, around 16-30% depending on age and gender.
We have shown that a notable proportion of neurological patients report psychiatric symptoms, thus emphasizing the importance of a thorough, multidimensional psychiatric screening in neurological patients.
DRKS00030528, date of registration: 2022-11-04 retrospectively registered.
虽然已知神经科患者患有精神疾病共病，但临床实践中仍缺乏合适、具有成本效益的标准化筛查措施。我们对神经科患者进行了一项多维度精神科筛查。
我们报告了一项对437例连续入住神经科的患者使用医院焦虑抑郁量表-抑郁分量表（HADS-D）和简明症状量表-53项版（BSI-53）进行多维度精神科筛查的回顾性分析。HADS-D描述抑郁和焦虑症状，而BSI-53通过躯体化、强迫观念与行为、人际敏感、敌对、偏执观念、精神病性及精神痛苦的总体测量来扩展与精神障碍相关的症状群。根据诊断将患者分为诊断组（血管性、脱髓鞘性、退行性、癫痫性、其他）。
我们的结果证实了先前的研究结果，即精神症状的高患病率尤其在年轻患者（<60岁）中。此外，27.2%的患者焦虑得分高于HADS-D临界值，25.4%的患者抑郁得分高于临界值。我们发现诊断组之间没有差异。重要的是，我们还表明神经科患者除了焦虑和抑郁外还存在精神痛苦，根据年龄和性别，这一比例约为16%-30%。
我们已经表明，相当一部分神经科患者报告有精神症状，因此强调了对神经科患者进行全面、多维度精神科筛查的重要性。
DRKS00030528，注册日期：2022年11月4日（追溯注册）
