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一种用于在护理点筛查和治疗宫颈癌及癌前病变的新型且经济高效的模式。

A novel and cost-effective model to screen and treat cervical cancer and precancers at the point of care.

作者信息

Bouquet Jean M, Morris Emily, Zapata Isain

机构信息

Department of Primary Care Medicine, Rocky Vista University College of Osteopathic Medicine, Englewood, CO, United States.

Rocky Vista University College of Osteopathic Medicine, Englewood, CO, United States.

出版信息

Front Public Health. 2025 Apr 16;13:1527172. doi: 10.3389/fpubh.2025.1527172. eCollection 2025.

DOI:10.3389/fpubh.2025.1527172
PMID:40308928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12042702/
Abstract

BACKGROUND

Cervical cancer has a high incidence to high mortality rate and poses an important global burden that disproportionately affects women in underdeveloped areas of the world. The World Health Organization has proposed a new and ambitious policy that aims to reduce the number of deaths from cervical cancer by 62.6 million over the next 70 years. However, there are many obstacles to the adoption of this policy and implementation in both Resource-Rich and Resource-Constrained Countries.

METHODS

In this perspective article, we propose a cost-effective, sustainable, and practical model that introduces a kit that may help overcome some of the existing barriers and achieve the goal to eventually eliminate cervical cancer. The kit includes a novel vaginal speculum that provides better visibility of the cervix, ease-of-use, and patient comfort; AI-assisted cervicography with a portable colposcope or Smart Phone; and canister-based cryotherapy.

RESULTS

Previous studies in Peru, Panama, Paraguay, and Kenya have demonstrated that these kits represent a novel, cost-effective, practical, accurate, and sustainable model to screen, triage, and treat cervical cancer and precancers at the point of care anywhere in the world.

CONCLUSION

This model is a simple and inexpensive solution to some of the barriers to care for cervical health, potentially providing significant benefits by decreasing morbidity and mortality of cervical cancer without significant risk for women throughout the world.

摘要

背景

宫颈癌发病率和死亡率都很高,给全球带来了重大负担,对世界欠发达地区的女性影响尤甚。世界卫生组织提出了一项新的宏伟政策,目标是在未来70年内将宫颈癌死亡人数减少6260万。然而,在资源丰富和资源有限的国家,采用和实施这项政策都存在诸多障碍。

方法

在这篇观点文章中,我们提出了一个具有成本效益、可持续且实用的模式,引入一种工具包,它可能有助于克服一些现有障碍,并实现最终消除宫颈癌的目标。该工具包包括一种新型阴道窥器,能更好地观察宫颈,使用方便,患者舒适度高;配备便携式阴道镜或智能手机的人工智能辅助宫颈成像;以及基于罐的冷冻疗法。

结果

此前在秘鲁、巴拿马、巴拉圭和肯尼亚进行的研究表明,这些工具包代表了一种新颖、经济高效、实用、准确且可持续的模式,可在世界任何地方的医疗点对宫颈癌和癌前病变进行筛查、分流和治疗。

结论

该模式是解决宫颈健康护理一些障碍的简单且经济的方案,有可能通过降低宫颈癌的发病率和死亡率为全球女性带来显著益处,且风险不大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd42/12042702/7575ff49d01a/fpubh-13-1527172-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd42/12042702/7575ff49d01a/fpubh-13-1527172-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd42/12042702/7575ff49d01a/fpubh-13-1527172-g0001.jpg

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Benefits, harms and cost-effectiveness of cervical screening, triage and treatment strategies for women in the general population.普通人群中女性宫颈筛查、分流和治疗策略的获益、危害和成本效益。
Nat Med. 2023 Dec;29(12):3050-3058. doi: 10.1038/s41591-023-02600-4. Epub 2023 Dec 12.
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An Innovative Design for the Vaginal Speculum.
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Artificial intelligence and visual inspection in cervical cancer screening.人工智能和宫颈癌筛查中的目视检查。
Int J Gynecol Cancer. 2023 Oct 2;33(10):1515-1521. doi: 10.1136/ijgc-2023-004397.
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