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尼日利亚南部农村代谢综合征患者中高血压和2型糖尿病的患病率:性别和年龄差异

Prevalence of Hypertension and Type 2 Diabetes Mellitus among Patients with Metabolic Syndrome in Rural Southern Nigeria: Gender and Age Disparities.

作者信息

Ibezim Harmony Uchenna, Njoya Helen Kwipnchep, Esene Hendrith, Azenabor Shalom Enahoro, Sule Saeed

机构信息

Department of Internal Medicine, Igbinedion University Teaching Hospital, Okada, Edo State, Nigeria.

Department of Biochemistry, Igbinedion University, Okada, Edo State, Nigeria.

出版信息

Niger Med J. 2025 Apr 3;66(1):279-289. doi: 10.71480/nmj.v66i1.706. eCollection 2025 Jan-Feb.

DOI:10.71480/nmj.v66i1.706
PMID:40309528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12038630/
Abstract

BACKGROUND

Metabolic syndrome (MetS) is a cluster of interconnected risk factors, including obesity, hypertension, elevated blood sugar, and abnormal lipid profiles. Its increasing prevalence globally poses a significant public health concern. This study investigated the prevalence of hypertension and type 2 diabetes mellitus (T2DM) in patients with MetS, considering age and gender in a rural teaching hospital.

METHODOLOGY

Conducted at Igbinedion University Teaching Hospital, Edo State, the study involved 75 patients selected through simple random sampling using the 2009 Joint Interim Statement (JIS) criteria of the IDF/AHA/NHLBI. It utilised an observational, cross-sectional, and retrospective design, focusing on individuals aged 18 years and older who consented to participate. Data was analysed using IBM SPSS version 23, with p < 0.05 considered significant.

RESULTS

The findings indicated that 60% of patients with MetS had hypertension, 17.3% had T2DM, and 22.7% were diagnosed with both conditions. Among hypertensive patients, 57.3% were female (P = 0.110). For T2DM, 25.3% of patients were female (P = 0.766). The prevalence of both T2DM (P = 0.106) and hypertension (P = 0.708) was higher in middle-aged patients compared to other age groups.

CONCLUSION

This study highlights the significant prevalence of hypertension and T2DM among patients with MetS in a rural teaching hospital, with notable variations across gender and age groups. While hypertension was more common in females, T2DM showed no significant gender disparity. Middle-aged individuals exhibited a higher prevalence of both conditions, underscoring the need for targeted screening and intervention strategies in this demographic.

摘要

背景

代谢综合征(MetS)是一组相互关联的危险因素,包括肥胖、高血压、血糖升高和血脂异常。其在全球范围内的患病率不断上升,引起了重大的公共卫生关注。本研究在一家农村教学医院中,考虑年龄和性别因素,调查了代谢综合征患者中高血压和2型糖尿病(T2DM)的患病率。

方法

该研究在江户州伊格贝尼迪翁大学教学医院进行,纳入了75例患者,这些患者通过简单随机抽样选取,采用国际糖尿病联盟(IDF)/美国心脏协会(AHA)/美国国立心肺血液研究所(NHLBI)2009年联合临时声明(JIS)标准。研究采用观察性、横断面和回顾性设计,重点关注18岁及以上同意参与的个体。使用IBM SPSS 23版软件进行数据分析,p<0.05被视为具有统计学意义。

结果

研究结果表明,60%的代谢综合征患者患有高血压,17.3%患有T2DM,22.7%同时被诊断出患有这两种疾病。在高血压患者中,57.3%为女性(P=

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