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尼日利亚北部一家医院终末期肾病血液透析患者的人口统计学和临床特征:模式与结局的回顾性分析

Demographic and Clinical Profile of Haemodialysis Patients with End-Stage Renal Disease in a Northern Nigerian Hospital: A Retrospective Analysis of Patterns and Outcomes.

作者信息

Abdulrasheed Muhammad, Armiyau Mohammed Bello, Abdullahi Yusuf Nadabo, Nuhu Maryam Kuso

机构信息

Department of Medicine, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

Yusuf Dantsoho Memorial General Hospital Tudun Wada, Kaduna, Nigeria.

出版信息

Niger Med J. 2025 Apr 3;66(1):165-173. doi: 10.71480/nmj.v66i1.660. eCollection 2025 Jan-Feb.

Abstract

BACKGROUND

Chronic kidney disease (CKD) is a global health challenge with increasing prevalence and substantial impacts on healthcare systems, particularly in low- and middle-income countries. Limited access to resources for managing CKD and end-stage renal disease (ESRD) in these regions exacerbates mortality and morbidity, highlighting the need for effective and accessible healthcare strategies. This study examines CKD prevalence, management practices, and outcomes across various populations, with a focus on the challenges faced in sub-Saharan Africa.

METHODOLOGY

This study utilized a retrospective, observational design to examine patient records from the haemodialysis unit at Yusuf Dantsoho Memorial General Hospital, Kaduna State, Nigeria. The research focused on the sociodemographic, clinical, and dialysis-related characteristics of patients who underwent haemodialysis between January 2019 and October 2024.

RESULTS

CKD prevalence has significantly increased worldwide, with ESRD incidence notably in our centre. Access to dialysis varied greatly, with low-resource settings struggling to meet demand, contributing to poorer outcomes. In Africa, studies show that less than 10% of patients who needed dialysis accessed it. Additionally, CKD patients in lower-income regions often present with advanced diseases due to inadequate screening and preventive care. High mortality rates were linked to limited access to early treatment and a lack of government support for subsidizing renal care.

CONCLUSION

There was a pressing need to improve CKD prevention, early diagnosis, and treatment in resource-limited settings to reduce the burden of ESRD. Increased government investment, enhanced screening programs, and sustainable funding models for dialysis were essential to mitigate the impact of CKD.

摘要

背景

慢性肾脏病(CKD)是一项全球性的健康挑战,其患病率不断上升,对医疗保健系统产生了重大影响,在低收入和中等收入国家尤为如此。这些地区用于管理CKD和终末期肾病(ESRD)的资源有限,这加剧了死亡率和发病率,凸显了制定有效且可及的医疗保健策略的必要性。本研究调查了不同人群中的CKD患病率、管理实践及结果,重点关注撒哈拉以南非洲地区所面临的挑战。

方法

本研究采用回顾性观察设计,以审查尼日利亚卡杜纳州优素福·丹特索霍纪念综合医院血液透析科的患者记录。该研究聚焦于2019年1月至2024年10月期间接受血液透析的患者的社会人口统计学、临床及透析相关特征。

结果

全球范围内CKD患病率显著上升,在我们中心ESRD发病率尤其明显。透析服务的可及性差异很大,资源匮乏地区难以满足需求,导致治疗结果较差。在非洲,研究表明,需要透析的患者中只有不到10%能够获得透析服务。此外,由于筛查和预防保健不足,低收入地区的CKD患者往往病情已发展到晚期。高死亡率与早期治疗机会有限以及政府缺乏对肾脏护理补贴的支持有关。

结论

迫切需要在资源有限的环境中改善CKD的预防、早期诊断和治疗,以减轻ESRD的负担。增加政府投资、加强筛查项目以及建立可持续的透析资金模式对于减轻CKD的影响至关重要。

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本文引用的文献

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Hemodialysis in Asia.亚洲的血液透析。
Kidney Dis (Basel). 2015 Dec;1(3):165-77. doi: 10.1159/000441816. Epub 2015 Nov 18.
4
Chronic kidney disease: global dimension and perspectives.慢性肾脏病:全球维度与展望。
Lancet. 2013 Jul 20;382(9888):260-72. doi: 10.1016/S0140-6736(13)60687-X. Epub 2013 May 31.
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US Renal Data System 2010 Annual Data Report.美国肾脏数据系统2010年年报。
Am J Kidney Dis. 2011 Jan;57(1 Suppl 1):A8, e1-526. doi: 10.1053/j.ajkd.2010.10.007.

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