Sadabadi Fatemeh, Talkhi Nasrin, Omouri-Kharashtomi Mahyaar, Mirzaei Mohammad, Saffar Soflaei Sara, Rahimi Zahra, Shabani Niloofar, Latifi MohammadReza, Mohammadtaghizadeh Sarabi Mohammadreza, Iri Sarina, Moghaddas Elham, Ferns Gordon A, Esmaily Habibollah, Ghayour-Mobarhan Majid
Metabolic Syndrome Research Center Mashhad University of Medical Sciences Mashhad Iran.
Department of Biostatistics, School of Health Tehran University of Medical Sciences Tehran Iran.
Health Sci Rep. 2025 Apr 29;8(5):e70721. doi: 10.1002/hsr2.70721. eCollection 2025 May.
Socio-economic status (SES) has been shown to be associated with cardiovascular disease. We aimed to investigate the relationship between SES and traditional risk factors for cardiovascular diseases in 35 to 65 adults of the MASHAD cohort study drawn from the second biggest city in Iran, Mashhad with a population of almost 3 million.
In this cross-sectional study, subjects were divided into three categories of SES status based on their education level, employment status, and monthly income using latent class analysis (LCA). The three SES of low, medium, and high classes were compared in terms of cardiovascular disease risk factors including diabetes mellitus, metabolic syndrome, obesity, dyslipidemia, and hypertension. value less than 0.05 was considered as significant.
A total number of 9704 participants were included in the study. According to goodness-of-fit measures and entropy the three-class model is the most optimal and suitable model here. Participants with a low SES had significantly lower means of age, physical activity level, waist circumference, systolic blood pressure and LDL-C, and higher means of weight, and hip circumferences. Also, the prevalence of smoking, hypertension and metabolic syndrome were lower in low SES group than the two other groups. Logistic regression showed that the odds of obesity in the high SES class was 1.3-fold higher than for the middle SES class. Moreover, the chance of metabolic syndrome and hypertension in the low SES class was respectively 0.81 and 0.83 of the middle SES class.
Lower socio-economic was associated with metabolic syndrome and hypertension and obesity was associated with higher SES; it may therefore be necessary to develop more specific and personalized preventive policies for populations in each socio-economic class.
社会经济地位(SES)已被证明与心血管疾病有关。我们旨在调查来自伊朗第二大城市马什哈德(人口近300万)的马什哈德队列研究中35至65岁成年人的SES与心血管疾病传统危险因素之间的关系。
在这项横断面研究中,使用潜在类别分析(LCA)根据受试者的教育水平、就业状况和月收入将其分为三类SES状态。比较了低、中、高三个SES类别在心血管疾病危险因素(包括糖尿病、代谢综合征、肥胖、血脂异常和高血压)方面的情况。P值小于0.05被认为具有统计学意义。
该研究共纳入9704名参与者。根据拟合优度测量和熵,三类模型是此处最优化和最合适的模型。SES较低的参与者年龄、身体活动水平、腰围、收缩压和低密度脂蛋白胆固醇(LDL-C)的均值显著较低,而体重和臀围的均值较高。此外,低SES组的吸烟、高血压和代谢综合征患病率低于其他两组。逻辑回归显示,高SES阶层肥胖的几率比中SES阶层高1.3倍。此外,低SES阶层患代谢综合征和高血压的几率分别是中SES阶层的0.81倍和0.83倍。
较低的社会经济地位与代谢综合征和高血压相关,而肥胖与较高的SES相关;因此,可能有必要为每个社会经济阶层的人群制定更具体和个性化的预防政策。