Liu Xinxing, Ding Guojian, Tian Wenchao, Liu Xijie, Fu Tingliang, Liu Hongzhen, Xu Aiqun, Han Xinling, Feng Wenyu, Geng Lei
Department of Pediatric Surgery, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Department of Pediatric Surgery, Children's Hospital Affiliated to Shandong University, Jinan, China.
Front Med (Lausanne). 2025 Apr 16;12:1509477. doi: 10.3389/fmed.2025.1509477. eCollection 2025.
Intrauterine ovarian torsion with autoamputation (IOTA) in fetuses was uncommon. The vague and non-specific symptomatology of IOTA makes early diagnosis challenging. Potential complications, such as hemorrhagic infarction of the adnexal structures with the subsequent sequelae, may occur. Moreover, therapeutic options, such as conservative or surgical management, for IOTA remain uncertain in the literature. We report three cases of IOTA, two of which were complicated by peritoneal adhesion or spontaneous bacterial peritonitis, confirmed surgically and through laboratory studies. A suspected diagnosis of this uncommon condition was made preoperatively in two cases. Our case reports provided additional information about this rare condition, including the occurrence of complicated bacterial peritonitis, in neonates and infants with IOTA. A review of the literature on imaging diagnosis and management options for IOTA is also included.
胎儿宫内卵巢扭转伴自截（IOTA）并不常见。IOTA模糊且非特异性的症状学表现使得早期诊断具有挑战性。可能会出现诸如附件结构出血性梗死及后续后遗症等潜在并发症。此外，IOTA的治疗选择，如保守治疗或手术治疗，在文献中仍不明确。我们报告了3例IOTA病例，其中2例并发腹膜粘连或自发性细菌性腹膜炎，经手术及实验室检查确诊。2例术前作出了这种罕见病症的疑似诊断。我们的病例报告提供了关于这种罕见病症的更多信息，包括IOTA新生儿和婴儿并发细菌性腹膜炎的情况。本文还包括对IOTA影像诊断及治疗选择的文献综述。
