Li Mengmeng, Huang Chaoyuan, Xing Hailun, Luo Shijuan, Lin Yiqun, Kuang Yuxiang, Wang Jing, Huang Suiping, Ye Zhenhao
The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Department of Gastroenterology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Front Med (Lausanne). 2025 Apr 16;12:1577291. doi: 10.3389/fmed.2025.1577291. eCollection 2025.
Henoch-Schönlein Purpura (HSP) is an acute systemic vasculitis that primarily affects the skin, gastrointestinal tract, kidneys and joints. It predominantly occurs in children but can occur at any age. We report a case of 48-year-old male patient suffering from unexplained epigastric pain alternating between relapses and remissions. The patient's initial clinical manifestation was atypical, starting with severe epigastric pain, without cutaneous purpura, and with normal rheumatologic and immunologic markers, making diagnosis difficult. The patient was eventually diagnosed with HSP. This case highlights the importance of considering this diagnosis in patients with unexplained abdominal pain and emphasize the role of endoscopy in diagnosing complex cases.
过敏性紫癜（HSP）是一种急性全身性血管炎，主要影响皮肤、胃肠道、肾脏和关节。它主要发生于儿童，但可发生于任何年龄。我们报告一例48岁男性患者，患有原因不明的上腹部疼痛，呈发作与缓解交替。患者最初的临床表现不典型，以严重上腹部疼痛起病，无皮肤紫癜，且风湿和免疫指标正常，诊断困难。该患者最终被诊断为过敏性紫癜。本病例强调了在不明原因腹痛患者中考虑这一诊断的重要性，并强调了内镜检查在诊断复杂病例中的作用。
