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以迟发性皮肤病变为表现的过敏性紫癜患者突发剧烈腹痛。

Paroxysmal drastic abdominal pain with tardive cutaneous lesions presenting in Henoch-Schönlein purpura.

机构信息

Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.

出版信息

World J Gastroenterol. 2012 Apr 28;18(16):1991-5. doi: 10.3748/wjg.v18.i16.1991.

DOI:10.3748/wjg.v18.i16.1991
PMID:22563183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3337578/
Abstract

Henoch-Schönlein purpura (HSP) is a small-vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. The diagnosis of HSP is difficult, especially when abdominal symptoms precede cutaneous lesions. We report a rare case of paroxysmal drastic abdominal pain with gastrointestinal bleeding presented in HSP. The diagnosis was verified by renal damage and the occurrence of purpura.

摘要

过敏性紫癜(HSP)是一种由 IgA 免疫复合物沉积介导的小血管血管炎。其特征是临床四联征,即非血小板减少性可触及性紫癜、腹痛、关节炎和肾脏受累。HSP 的诊断困难,尤其是当腹部症状先于皮肤损伤出现时。我们报告了 HSP 中罕见的阵发性剧烈腹痛伴胃肠道出血的病例。诊断通过肾损伤和紫癜的发生得到证实。

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本文引用的文献

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J Med Case Rep. 2011 Aug 10;5:364. doi: 10.1186/1752-1947-5-364.
2
The clinical implications of adult-onset henoch-schonelin purpura.成人过敏性紫癜的临床意义。
Clin Mol Allergy. 2011 May 27;9(1):9. doi: 10.1186/1476-7961-9-9.
3
Henoch-Schönlein purpura complicating adalimumab therapy for Crohn's disease.亨诺-许兰紫癜并发阿达木单抗治疗克罗恩病。
World J Gastrointest Pharmacol Ther. 2010 Oct 6;1(5):119-22. doi: 10.4292/wjgpt.v1.i5.119.
4
Henoch-Schonlein purpura nephritis: pathophysiology, treatment, and future strategy.过敏性紫癜性肾炎:发病机制、治疗和未来策略。
Clin J Am Soc Nephrol. 2011 Mar;6(3):679-89. doi: 10.2215/CJN.06710810. Epub 2011 Mar 10.
5
Henoch-schonlein purpura-a case report and review of the literature.过敏性紫癜病例报告及文献复习。
Gastroenterol Res Pract. 2010;2010:597648. doi: 10.1155/2010/597648. Epub 2010 May 23.
6
Henoch-Schönlein purpura.过敏性紫癜。
Curr Opin Rheumatol. 2010 Sep;22(5):598-602. doi: 10.1097/BOR.0b013e32833af608.
7
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Digestion. 2008;77(3-4):236-41. doi: 10.1159/000150697. Epub 2008 Aug 7.
8
Gastrointestinal manifestations of Henoch-Schonlein Purpura.过敏性紫癜的胃肠道表现
Dig Dis Sci. 2008 Aug;53(8):2011-9. doi: 10.1007/s10620-007-0147-0. Epub 2008 Mar 20.
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