Babapour Sara, Chen Annabel, Li Grace, Phan Luke
Radiological Sciences, Clinical Research, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Ave, Los Angeles, CA 90095, USA.
Diagnostics (Basel). 2025 Apr 10;15(8):960. doi: 10.3390/diagnostics15080960.
Identifying patterns of diagnostic imaging workflow parallel to the influence of certain variables, such as pathology guidelines over time, provides valuable insight for clinical decision making. This study presents a recurring trend of initial imaging orders and follow-ups, up to the diagnosis of pancreatic neuroendocrine tumors (pNETs), across two decades, with scans which led to pathological investigation. Three readers evaluated common conventional imaging among initial and follow-up studies for lesion detection and localization. Inter-reader and intra-reader analyses were controlled as contributing factors to the imaging diagnostic trend. Our results show that CT was the prominent initial scan in pNET workup, likely due to their wide availability, high spatial resolution, and rapid acquisition, with a sufficient detection rate throughout both decades, regardless of technical advances. However, MRI scans also gained soaring popularity, especially among syndromic patients, likely due to follow-up and anatomical surgery precision. Newer modalities may be eventually useful and only requested for pNETs staging and further treatment.
识别与某些变量（如随时间变化的病理学指南）影响并行的诊断成像工作流程模式，为临床决策提供了有价值的见解。本研究呈现了二十年间直至胰腺神经内分泌肿瘤（pNETs）诊断的初始成像检查和后续检查的反复趋势，这些扫描导致了病理检查。三位阅片者评估了初始和后续研究中用于病变检测和定位的常见传统成像。阅片者间和阅片者内分析作为成像诊断趋势的影响因素受到控制。我们的结果表明，CT是pNET检查中突出的初始扫描方式，这可能是由于其广泛可用性、高空间分辨率和快速采集，在这二十年中无论技术进步如何都具有足够的检测率。然而，MRI扫描也越来越受欢迎，尤其是在综合征患者中，这可能是由于随访和解剖手术的精确性。更新的检查方式最终可能有用，仅用于pNETs分期和进一步治疗。
