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关节镜辅助下单通道脊柱手术治疗伴侧隐窝狭窄的腰椎间盘突出症的隐性失血及临床疗效评估

Evaluation of Hidden Blood Loss and Clinical Outcomes of Arthroscopy-Assisted Uni-Portal Spinal Surgery for Lumbar Disc Herniation with Lateral Recess Stenosis.

作者信息

Zhou Shihao, Xu Xiaowan, Hu Peiran, Guo Tianluo, Zhao Hongshun, Xu Zhihua, Gao Tengjun, Hao Yan, Tie Haoliang

机构信息

Graduate School of Qinghai University, Xining, Qinghai Province, China; Department of Spine Surgery, Qinghai Red Cross Hospital, Xining, Qinghai Province, China.

Department of Spine Surgery, Qinghai Red Cross Hospital, Xining, Qinghai Province, China.

出版信息

World Neurosurg. 2025 Jun;198:124026. doi: 10.1016/j.wneu.2025.124026. Epub 2025 Apr 29.

Abstract

OBJECTIVE

This study aims to evaluate hidden blood loss (HBL) and its influencing factors in patients with lumbar disc herniation-related lateral recess stenosis who underwent arthroscopy-assisted uni-portal spinal surgery (AUSS). Additionally, the study assesses clinical outcomes at the 6-month postoperative follow-up.

METHODS

This study included 129 patients with lumbar disc herniation-associated lateral recess stenosis who underwent AUSS during the year 2024. Demographic data and parameters related to blood loss were recorded. HBL was calculated using the Nadler and Gross formulas. Pearson or Spearman correlation analyses were performed to explore the relationships between patient characteristics and HBL. Multiple linear regression analysis was used to identify independent risk factors for HBL. Primary clinical outcomes (visual analog scale scores) and secondary outcomes (Oswestry Disability Index scores and the modified Macnab criteria) were assessed preoperatively and at 3 days, 3 months, and 6 months postoperatively. Longitudinal data were analyzed using generalized mixed linear models.

RESULTS

A total of 129 consecutive patients (66 females and 63 males) were enrolled. The average HBL was 414.34 ± 179.15 ml. Correlation analyses (Pearson and Spearman) revealed significant associations between surgical duration, American Society of Anesthesiologists (ASA) score, muscle thickness, preoperative activated partial thromboplastin time, and preoperative D-dimer with HBL (P < 0.05). Multiple linear regression analysis identified surgical duration and ASA score as independent risk factors for HBL. Postoperative visual analog scale and Oswestry Disability Index scores showed significant improvement compared to preoperative values.

CONCLUSIONS

The amount of HBL in patients undergoing AUSS should not be underestimated. ASA score and surgical duration are independent risk factors for HBL. AUSS, as an improved technique, significantly alleviates postoperative pain and enhances quality of life, demonstrating good short-term clinical efficacy. It is an effective treatment option for lateral recess stenosis caused by lumbar disc herniation.

摘要

目的

本研究旨在评估接受关节镜辅助单通道脊柱手术(AUSS)的腰椎间盘突出症相关侧隐窝狭窄患者的隐性失血(HBL)及其影响因素。此外,该研究还评估术后6个月随访时的临床结局。

方法

本研究纳入了2024年期间接受AUSS的129例腰椎间盘突出症合并侧隐窝狭窄患者。记录人口统计学数据和与失血相关的参数。使用Nadler和Gross公式计算HBL。进行Pearson或Spearman相关性分析以探讨患者特征与HBL之间的关系。采用多元线性回归分析确定HBL的独立危险因素。术前及术后3天、3个月和6个月评估主要临床结局(视觉模拟量表评分)和次要结局(Oswestry功能障碍指数评分和改良Macnab标准)。使用广义混合线性模型分析纵向数据。

结果

共纳入129例连续患者(66例女性和63例男性)。平均HBL为414.34±179.15 ml。相关性分析(Pearson和Spearman)显示手术时间、美国麻醉医师协会(ASA)评分、肌肉厚度、术前活化部分凝血活酶时间和术前D-二聚体与HBL之间存在显著相关性(P<0.05)。多元线性回归分析确定手术时间和ASA评分是HBL的独立危险因素。术后视觉模拟量表和Oswestry功能障碍指数评分与术前值相比有显著改善。

结论

接受AUSS患者的HBL量不应被低估。ASA评分和手术时间是HBL的独立危险因素。AUSS作为一种改良技术,能显著减轻术后疼痛并提高生活质量,显示出良好的短期临床疗效。它是治疗腰椎间盘突出症所致侧隐窝狭窄的有效治疗选择。

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