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内镜减压联合经皮椎弓根螺钉固定治疗伴有神经功能缺损的AOSpine A3或A4型胸腰椎骨折:一项回顾性队列研究

Endoscopic Decompression Combined With Percutaneous Pedicle Screw Fixation for AOSpine A3 or A4 Thoracolumbar Fractures With Neurological Deficits: A Retrospective Cohort Study.

作者信息

Yang Huiming, Miao Junxian, Wang Jiangtao, Han Dan, Wang Yuhang, Yan Liang, Wang Biao, Hao Dingjun

机构信息

Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, China.

Shaanxi University of Chinese Medicine, Xianyang, China.

出版信息

Neurospine. 2025 Jun;22(2):571-582. doi: 10.14245/ns.2449212.606. Epub 2025 Apr 30.

Abstract

OBJECTIVE

This study aimed to compare the clinical outcomes of patients with AOSpine A3 or A4 thoracolumbar fractures presenting with neurological deficits treated with endoscopic decompression combined with percutaneous pedicle screws fixation (endoscopic minimally invasive surgery, EMIS) or conventional open surgery (OS).

METHODS

Data of patients with AOSpine A3 or A4 thoracolumbar fractures with neurological deficits who were treated with EMIS or OS between June 2019 and July 2021 were extracted from the electronic database. Various clinical outcomes were compared between the 2 cohorts.

RESULTS

Among the 231 patients who were followed up for more than 2 years, 107 were in the EMIS cohort and 124 were in the OS cohort. Compared with the OS cohort, the EMIS cohort had longer operative time (p<0.05), but the intraoperative blood loss, incision length and hospital stay were significantly reduced (p<0.05). At both postoperative and final follow-up assessments, the EMIS cohort demonstrated significantly better visual analogue scale and Oswestry Disability Index outcomes compared to the OS cohort (p<0.05). Both cohorts maintained similar correction of spinal canal erosion rate, percentage of anterior vertebral height and sagittal Cobb angle after surgery and at the last follow-up (p>0.05). According to American Spinal Injury Association classification, the 2 cohorts had similar neurological recovery at the last follow-up (p>0.05).

CONCLUSION

In comparison to OS, EMIS treatment for AOSpine A3 or A4 thoracolumbar fractures with neurological deficits has shown comparable clinical efficacy while significantly reducing surgical trauma.

摘要

目的

本研究旨在比较采用内镜减压联合经皮椎弓根螺钉固定术(内镜微创手术,EMIS)或传统开放手术(OS)治疗伴有神经功能缺损的AOSpine A3或A4型胸腰椎骨折患者的临床疗效。

方法

从电子数据库中提取2019年6月至2021年7月期间接受EMIS或OS治疗的伴有神经功能缺损的AOSpine A3或A4型胸腰椎骨折患者的数据。比较两组患者的各项临床疗效。

结果

在231例随访超过2年的患者中,EMIS组107例,OS组124例。与OS组相比,EMIS组手术时间更长(p<0.05),但术中出血量、切口长度和住院时间显著减少(p<0.05)。在术后及末次随访评估中,EMIS组的视觉模拟评分和Oswestry功能障碍指数结果均显著优于OS组(p<0.05)。两组在术后及末次随访时椎管侵蚀率、椎体前缘高度百分比和矢状面Cobb角的矫正情况均相似(p>0.05)。根据美国脊髓损伤协会分类,两组在末次随访时神经功能恢复情况相似(p>0.05)。

结论

与OS相比,EMIS治疗伴有神经功能缺损的AOSpine A3或A4型胸腰椎骨折临床疗效相当,但手术创伤显著减小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8d3/12242755/8fc2e564d9b6/ns-2449212-606f1.jpg

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