Alagappan Arthi, Muthu Jananni, Ravindran Saravanakumar, Balu Pratebha, Ramkumar Narayane, Arulanandan Sushma
Department of Periodontology, Indira Gandhi Institute of Dental Sciences, Mahatma Gandhi Medical College and Research Institute Campus, Sri Balaji Vidyapeeth University, Puducherry, India.
J Indian Soc Periodontol. 2024 Nov-Dec;28(6):685-690. doi: 10.4103/jisp.jisp_119_24. Epub 2025 Apr 3.
Insufficient width of keratinized gingiva (WKG) leads to clinical attachment loss (CAL) and eventually periodontal destruction. Free gingival graft (FGG) is the gold standard to increase WKG but requires a second surgical site and poor esthetics outcomes. Hence, alternatives like collagen matrix (CM) have been developed.
The present study aims to evaluate the efficacy of CM versus FGG in augmenting WKG in the lower anterior.
Twenty patients with inadequate WKG were enrolled and allocated into two groups. Group I participants received augmentation of WKG using CM and Group II participants with FGG. Clinical parameters such as probing pocket depth, CAL, WKG, and gingival thickness were recorded at baseline, 3 month, and 6 month. Plaque score was recorded at baseline and 6 month and wound healing index was recorded at 14 and 21 days. The parameters within the group and between the groups were compared using repeated measures of analysis of variance and independent -test.
The mean WKG of Group I and Group II in 6 month after augmentation was 3.88 ± 0.3 mm and 5.21 ± 1.0 mm, respectively, and the difference was statistically significant ( = 0.001). The mean wound healing index for Group I and Group II measured on 21 day was 5.00 ± 0.1 and 2.50 ± 0.5, respectively, and the difference in the wound healing index was statistically significant ( = 0.001).
Both CM and FGG are suitable for increasing the WKG. FGG aided in a marginally greater increase in WKG than CM and healing was better with CM as compared to FGG.
角化龈宽度不足（WKG）会导致临床附着丧失（CAL），最终引发牙周组织破坏。游离龈移植术（FGG）是增加WKG的金标准，但需要第二个手术部位且美学效果不佳。因此，已开发出胶原蛋白基质（CM）等替代方法。
本研究旨在评估CM与FGG在下前牙区增加WKG的疗效。
招募20例WKG不足的患者并分为两组。第一组患者使用CM增加WKG，第二组患者使用FGG。在基线、3个月和6个月时记录临床参数，如探诊深度、CAL、WKG和牙龈厚度。在基线和6个月时记录菌斑评分，在14天和21天时记录伤口愈合指数。使用重复测量方差分析和独立样本t检验比较组内和组间的参数。
术后6个月，第一组和第二组的平均WKG分别为3.88±0.3mm和5.21±1.0mm，差异具有统计学意义（P = 0.001）。在第21天测量的第一组和第二组的平均伤口愈合指数分别为5.00±0.1和2.50±0.5，伤口愈合指数的差异具有统计学意义（P = 0.001）。
CM和FGG均适用于增加WKG。FGG增加WKG的幅度略大于CM，与FGG相比，CM的愈合效果更好。
