高强度激光疗法治疗非特异性颈部疼痛的即时效果：一项双盲随机对照试验

Immediate effects of high-intensity laser therapy for nonspecific neck pain: a double-blind randomized controlled trial.

作者信息

Xie Yuhua, Diao Yingxiu, Wu Dongyu, Liao Manxia, Liao Linrong

机构信息

Gannan Healthcare Vocational College, Ganzhou, China.

Rehabilitation Medicine Center, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China.

出版信息

Front Med (Lausanne). 2025 Apr 11;12:1550047. doi: 10.3389/fmed.2025.1550047. eCollection 2025.

DOI:10.3389/fmed.2025.1550047

PMID:40313543

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12044425/

Abstract

OBJECTIVES

The objective of this research was to assess the immediate effects of high-intensity laser therapy (HILT) on nonspecific neck pain (NNP) by evaluating outcome measures such as pain intensity, cervical active range of motion (ROM), stiffness of neck muscles, and functional disability.

METHODS

This clinical trial, which was conducted in a double-blind and randomized manner, involved patients diagnosed with NNP who were allocated either to either a HILT group (HILT + exercise) or a placebo group (placebo-laser therapy + exercise). The primary outcome measures encompassed pain intensity via the visual analogue scale (VAS), cervical active ROM, stiffness of neck muscles (splenius capitis, semispinalis capitis, and neck fascia), as well as functional disability via the neck disability index (NDI). Statistical evaluations were carried out using SPSS version 25.0, with a significance threshold established at  < 0.05.

RESULTS

A total of 28 individuals diagnosed with NNP were randomly allocated to either the HILT group ( = 14) or the placebo group ( = 14). Upon initial comparison, no significant differences ( > 0.05) were observed between the two groups. After treatment, both groups showed notable improvements in all outcome measures compared to baseline ( < 0.05); moreover, the HILT group demonstrated greater efficacy compared to the placebo group in terms of VAS scores (29.64 ± 8.43 mm,  = 0.001), cervical lateral flexion (right 22.46 ± 3.62°,  = 0.011; left 22.34 ± 2.74°,  = 0.034) and neck muscle shear modulus (splenius capitis muscle 22.48 ± 4.03 kPa,  = 0.001; semispinalis capitis muscle 23.50 ± 5.59 kPa,  = 0.028); however, no statistically significant differences ( > 0.05) were identified between the groups in cervical flexion, extension, rotation, neck fascia stiffness and NDI scores.

CONCLUSION

HILT has immediate efficacy for NNP and may be considered as one of the alternative interventions for NNP.

CLINICAL TRIAL REGISTRATION

http://www.chictr.org.cn/, identifier ChiCTR2200061008.

摘要

目的

本研究的目的是通过评估疼痛强度、颈椎主动活动范围（ROM）、颈部肌肉僵硬程度和功能障碍等结果指标，来评估高强度激光疗法（HILT）对非特异性颈部疼痛（NNP）的即时效果。

方法

本临床试验采用双盲随机方式进行，纳入被诊断为NNP的患者，将其分为HILT组（HILT+运动）或安慰剂组（安慰剂激光疗法+运动）。主要结果指标包括通过视觉模拟量表（VAS）评估的疼痛强度、颈椎主动ROM、颈部肌肉（头夹肌、头半棘肌和颈部筋膜）的僵硬程度，以及通过颈部功能障碍指数（NDI）评估的功能障碍。使用SPSS 25.0版进行统计评估，显著性阈值设定为<0.05。

结果

共有28名被诊断为NNP的个体被随机分配到HILT组（=14）或安慰剂组（=14）。初始比较时，两组之间未观察到显著差异（>0.05）。治疗后，与基线相比，两组在所有结果指标上均有显著改善（<0.05）；此外，在VAS评分（29.64±8.43mm，=0.001）、颈椎侧屈（右侧22.46±3.62°，=0.011；左侧22.34±2.74°，=0.034）和颈部肌肉剪切模量（头夹肌22.48±4.03kPa，=0.001；头半棘肌23.50±5.59kPa，=0.028）方面，HILT组比安慰剂组显示出更大的疗效；然而，在颈椎前屈、后伸、旋转、颈部筋膜僵硬程度和NDI评分方面，两组之间未发现统计学显著差异（>0.05）。