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膀胱非典型颗粒细胞瘤——一种极其罕见肿瘤的病例报告

Atypical granular cell tumour of urinary bladder - case report of an extremely rare neoplasm.

作者信息

Muniak Dominika, Łaszczych Dariusz, Czernicka Aleksandra, Drewa Tomasz, Borowczak Jędrzej

机构信息

Department of Urology and Andrology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.

Department of General and Oncological Urology, University Hospital No. 1 in Bydgoszcz, Poland.

出版信息

Cent European J Urol. 2024;77(4):637-640. doi: 10.5173/ceju.2024.153. Epub 2024 Nov 10.

DOI:10.5173/ceju.2024.153
PMID:40313708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12042400/
Abstract

We report a case of a 59-year-old woman presenting with haematuria and suprapubic pain. Cystoscopy revealed a spherical lesion within the urinary bladder, which was subsequently removed by transurethral resection. Histopathology confirmed the diagnosis of an atypical granular cell tumour (AGCT). So far, during 12 months of follow-up, no evidence of tumour relapse has been detected. This article highlights the challenges associated with bladder AGCT, emphasising the importance of histopathological examination and appropriate management. Bladder AGCT presents with non-specific symptoms that delay its diagnosis. This case emphasises the need for further research to improve treatment and follow-up guidelines for bladder AGCT.

摘要

我们报告一例59岁女性,出现血尿和耻骨上疼痛。膀胱镜检查发现膀胱内有一个球形病变,随后经尿道切除术将其切除。组织病理学确诊为非典型颗粒细胞瘤(AGCT)。到目前为止,在12个月的随访期间,未发现肿瘤复发迹象。本文强调了膀胱AGCT相关的挑战,强调了组织病理学检查和适当管理的重要性。膀胱AGCT表现出非特异性症状,延误了其诊断。该病例强调需要进一步研究,以改进膀胱AGCT的治疗和随访指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c07/12042400/d0071be36d63/CEJU-77-2024.0153-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c07/12042400/2163293cc3ab/CEJU-77-2024.0153-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c07/12042400/d0071be36d63/CEJU-77-2024.0153-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c07/12042400/2163293cc3ab/CEJU-77-2024.0153-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c07/12042400/d0071be36d63/CEJU-77-2024.0153-g002.jpg

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本文引用的文献

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A case report of atypical granular cell tumor of bladder.膀胱非典型颗粒细胞瘤病例报告
Int J Surg Case Rep. 2024 Aug;121:109980. doi: 10.1016/j.ijscr.2024.109980. Epub 2024 Jul 1.
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Atypical granular cell tumor of the urinary bladder: A case report.膀胱非典型颗粒细胞瘤:一例报告。
World J Clin Cases. 2021 Oct 6;9(28):8453-8460. doi: 10.12998/wjcc.v9.i28.8453.
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European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (Ta, T1, and Carcinoma in Situ).欧洲泌尿外科学会非肌层浸润性膀胱癌(Ta、T1和原位癌)指南
Eur Urol. 2022 Jan;81(1):75-94. doi: 10.1016/j.eururo.2021.08.010. Epub 2021 Sep 10.
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Atypical granular cell tumor of the urinary bladder: A case report and literature review.膀胱非典型颗粒细胞瘤:一例报告及文献复习
Urol Case Rep. 2021 Mar 29;38:101669. doi: 10.1016/j.eucr.2021.101669. eCollection 2021 Sep.
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Granular Cell Tumor of the Bladder: A Report of Six Cases.膀胱颗粒细胞瘤:6例报告
Urology. 2018 Nov;121:203.e1-203.e5. doi: 10.1016/j.urology.2018.08.018. Epub 2018 Aug 29.
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