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青年成人后天性或遗传性心脏传导障碍:当前文献综述

Cardiac Conduction Disorders Due to Acquired or Genetic Causes in Young Adults: A Review of the Current Literature.

作者信息

Balla Cristina, Canovi Luca, Zuin Marco, Di Lenno Luca, Berloni Maria L, de Carolis Beatrice, Di Domenico Assunta, Tonet Elisabetta, Vitali Francesco, Malagu Michele, Boriani Giuseppe, Bertini Matteo

机构信息

Cardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.

Pediatric Cardiology and Adult Congenital Heart Disease Program, Department of Cardio-Thoracic and Vascular Medicine IRCCS Azienda Ospedaliero-Universitaria di Bologna Bologna Italy.

出版信息

J Am Heart Assoc. 2025 May 6;14(9):e040274. doi: 10.1161/JAHA.124.040274. Epub 2025 May 2.

Abstract

Cardiac conduction disorders can manifest in young adults in isolated forms, associated with myocardial diseases or as part of a multiorgan disorder. Underlying causes of cardiac conduction disorders may be genetically determined or acquired. Cardiac conduction disorder in young adults is a complex and often underestimated and underrecognized disease that may need of a multidisciplinary team for the diagnosis, treatment, and long-term management of these patients. Therefore, it is crucial to raise clinicians' awareness of this condition. In this review, we provide a comprehensive update on the cause, diagnosis, and treatment of young adults with cardiac conduction disorders, also suggesting potential strategies to improve the current clinical management of these patients.

摘要

心脏传导障碍在年轻人中可表现为孤立形式,与心肌病相关或作为多器官疾病的一部分。心脏传导障碍的潜在病因可能是遗传决定的或后天获得的。年轻人的心脏传导障碍是一种复杂且常被低估和认识不足的疾病,可能需要多学科团队对这些患者进行诊断、治疗和长期管理。因此,提高临床医生对这种疾病的认识至关重要。在本综述中,我们全面更新了有关年轻心脏传导障碍患者的病因、诊断和治疗的内容,还提出了改善这些患者当前临床管理的潜在策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b43d/12184228/2881789edc60/JAH3-14-e040274-g001.jpg

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