Lin Yunkun, He Wenjing, He Junwei, Liu Limei
Affiliated Hospital of Putian University, Putian, China.
Meizhouwan Vocational Technology College, Putian, China.
Clinics (Sao Paulo). 2025 May 2;80:100667. doi: 10.1016/j.clinsp.2025.100667. eCollection 2025.
Examination of the current status of acute fatigue in patients with acute ischemic stroke and analysis of contributing factors.
A convenience sampling method was utilized to recruit 420 patients diagnosed with acute ischemic stroke, who were admitted to the affiliated hospital of Putian University in Fujian Province, China, between October 2022 and December 2023. Data collection involved the administration of a general information questionnaire, the Fatigue Severity Scale (FSS), the Fear of Progression Questionnaire (FoP-Q-SF), the Perceived Social Support Scale (PSSS), the Barthel Index, and the Modified Rankin Scale (MRS).
The mean score for Post-stroke Fatigue (PSF) was 3.08 ± 1.52, and the prevalence rate of elevated PSF was 37.4 %. Unconditional logistic regression analysis revealed that social support functioned as a protective factor against fatigue in patients with acute ischemic stroke. Conversely, being female, having chronic comorbidities, having a stroke located in the basal ganglion, high Modified Rankin Scale (MRS) scores, poor self-care ability, and fear of disease progression were identified as risk factors for fatigue (p < 0.05 or p < 0.01).
Perceived Stress Factor (PSF) is a common and serious consequence following stroke, which considerably impacts patients' recovery and overall quality of life. Consequently, clinical practice should prioritize the identification and management of PSF through early intervention and targeted therapeutic strategies to enhance patient prognosis and quality of life. Additionally, further research is warranted to investigate the underlying biological mechanisms of PSF and to develop potential intervention strategies. This study adopted a cross-sectional research design.
调查急性缺血性脑卒中患者急性疲劳的现状并分析相关影响因素。
采用便利抽样法，选取2022年10月至2023年12月在中国福建省莆田学院附属医院收治的420例确诊为急性缺血性脑卒中的患者。数据收集包括发放一般信息问卷、疲劳严重程度量表（FSS）、疾病进展恐惧问卷（FoP-Q-SF）、领悟社会支持量表（PSSS）、巴氏指数和改良Rankin量表（MRS）。
脑卒中后疲劳（PSF）的平均得分为3.08±1.52，PSF升高的患病率为37.4%。无条件逻辑回归分析显示，社会支持是急性缺血性脑卒中患者疲劳的保护因素。相反，女性、患有慢性合并症、基底节区脑卒中、改良Rankin量表（MRS）评分高、自我护理能力差以及对疾病进展的恐惧被确定为疲劳的危险因素（p<0.05或p<0.01）。
感知应激因素（PSF）是脑卒中后常见且严重的后果，对患者的康复和整体生活质量有相当大的影响。因此，临床实践应通过早期干预和针对性治疗策略，优先识别和管理PSF，以改善患者预后和生活质量。此外，有必要进一步研究PSF的潜在生物学机制并制定潜在的干预策略。本研究采用横断面研究设计。
