Alhamdan Mai Mohammed
Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.
Photodiagnosis Photodyn Ther. 2025 Jun;53:104615. doi: 10.1016/j.pdpdt.2025.104615. Epub 2025 May 1.
To assess the influence of different root canal disinfectants i.e., Potassium titanyl phosphate laser (KTPL), Aloe-emodin (AE) mediated Photodynamic therapy (PDT), Magnesium oxide (MgO) nanoparticles (NPs) on smear layer (SL) removal and push out bond strength (PBS) of Glass fiber post (GFP) to the canal dentin.
Forty-eight extracted premolars, having a single root and a solitary canal were included. A root canal procedure was performed on each tooth and subsequently, post-space preparation was executed using peeso-reamers leaving approximately 4 mm of gutta percha in the canal. According to the type of disinfection used the samples were categorized into 4 groups (n = 11). Group 1 (2.5 % NaOCl + EDTA), Group 2 (KTPL+ EDTA), Group 3 (AE mediated PDT+ EDTA), and Group 4 (MgONPs+ EDTA). Cementation of fiber posts was performed using a self-adhesive resin cement. Scanning electron microscope (SEM) assessed the SL removal from the canals (n = 2). Failure mode and PBS were assessed with a stereomicroscope and universal testing machine respectively(n = 10). One-way analysis of variance and Tukey posthoc test at p-value ≤ 0.05 were used to compare the mean scores of PBS and SL removal.
The cervical region in Group 4 (MgONPs + EDTA) samples showed the highest PBS scores (10.41±0.38 MPa) and the maximum level of SL removal (1.55±0.10). Conversely, Group 3 at the apical third of the root (AE mediated PDT EDTA) displayed the least efficacy for SL removal (2.81±0.09) and lowest PBS(7.69±0.19 MPa).
MgO nanoparticles, when paired with Ethylenediaminetetraacetic acid as a final irrigant, offer a promising alternative to conventional root canal sterilants.
评估不同根管消毒剂,即磷酸氧钛钾激光(KTPL)、芦荟大黄素(AE)介导的光动力疗法(PDT)、氧化镁(MgO)纳米颗粒(NPs)对玷污层(SL)去除以及玻璃纤维桩(GFP)与根管牙本质之间推出粘结强度(PBS)的影响。
纳入48颗单根单管的拔除前磨牙。对每颗牙齿进行根管治疗,随后使用梨形根管扩大器进行桩道预备,在根管内保留约4mm的牙胶。根据所使用的消毒类型,将样本分为4组(n = 11)。第1组(2.5%次氯酸钠+乙二胺四乙酸),第2组(KTPL+乙二胺四乙酸),第3组(AE介导的PDT+乙二胺四乙酸),第4组(MgO纳米颗粒+乙二胺四乙酸)。使用自粘结树脂水门汀进行纤维桩的粘结。扫描电子显微镜(SEM)评估根管内SL的去除情况(n = 2)。分别使用体视显微镜和万能试验机评估失败模式和PBS(n = 10)。采用p值≤0.05的单因素方差分析和Tukey事后检验来比较PBS和SL去除的平均得分。
第4组(MgO纳米颗粒+乙二胺四乙酸)样本的颈部区域显示出最高的PBS得分(10.41±0.38MPa)和最大程度的SL去除(1.55±0.10)。相反,第3组在根尖三分之一处(AE介导的PDT乙二胺四乙酸)显示出最低的SL去除效果(2.81±0.09)和最低的PBS(7.69±0.19MPa)。
氧化镁纳米颗粒与乙二胺四乙酸作为最终冲洗液联合使用时,为传统根管消毒剂提供了一种有前景的替代方案。