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Airway Basal Stem Cell Population Is Enlarged in Bronchial Thermoplasty Treated Airways in Severe Asthma Patients.

作者信息

Gillett Tessa E, Vassileva Sofi M, Weersink Els, Annema Jouke, Lutter René, Nawijn Martijn C, van den Berge Maarten, Bonta Peter I, Ravi Abilash

机构信息

Experimental Pulmonary and Inflammatory Research, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

出版信息

Clin Exp Allergy. 2025 Sep;55(9):880-882. doi: 10.1111/cea.70071. Epub 2025 May 4.

DOI:10.1111/cea.70071
PMID:40320688
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12433732/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfe/12433732/5d60de8ee0d4/CEA-55-880-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfe/12433732/5d60de8ee0d4/CEA-55-880-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfe/12433732/5d60de8ee0d4/CEA-55-880-g001.jpg

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本文引用的文献

1
Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells.气道干细胞通过移植原代或多能干细胞衍生的基底细胞进行重建。
Cell Stem Cell. 2023 Sep 7;30(9):1199-1216.e7. doi: 10.1016/j.stem.2023.07.014. Epub 2023 Aug 24.
2
Comparing bronchial thermoplasty with biologicals for severe asthma: Systematic review and network meta-analysis.比较支气管热成形术与生物制剂治疗重度哮喘：系统评价与网状Meta分析。
Respir Med. 2023 Sep;216:107302. doi: 10.1016/j.rmed.2023.107302. Epub 2023 May 29.
3
Airway Inflammation Before and After Bronchial Thermoplasty in Severe Asthma.
重度哮喘患者支气管热成形术前及术后的气道炎症
J Asthma Allergy. 2022 Dec 16;15:1783-1794. doi: 10.2147/JAA.S383418. eCollection 2022.
4
Airway Basal Cells in Chronic Obstructive Pulmonary Disease: A Continuum or a Dead End?慢性阻塞性肺疾病中的气道基底细胞：是连续过程还是死胡同？
Am J Respir Cell Mol Biol. 2021 Jul;65(1):10-12. doi: 10.1165/rcmb.2021-0150ED.
5
Metabolic differences between bronchial epithelium from healthy individuals and patients with asthma and the effect of bronchial thermoplasty.支气管上皮细胞在健康个体、哮喘患者及支气管热成形术治疗患者之间的代谢差异。
J Allergy Clin Immunol. 2021 Nov;148(5):1236-1248. doi: 10.1016/j.jaci.2020.12.653. Epub 2021 Feb 6.
6
Bronchial Thermoplasty Induced Airway Smooth Muscle Reduction and Clinical Response in Severe Asthma. The TASMA Randomized Trial.支气管热成形术诱导的气道平滑肌减少与重度哮喘的临床反应。TASMA 随机试验。
Am J Respir Crit Care Med. 2021 Jan 15;203(2):175-184. doi: 10.1164/rccm.201911-2298OC.
7
A cellular census of human lungs identifies novel cell states in health and in asthma.对人类肺部的细胞普查鉴定了健康和哮喘中的新型细胞状态。
Nat Med. 2019 Jul;25(7):1153-1163. doi: 10.1038/s41591-019-0468-5. Epub 2019 Jun 17.
8
The prevalence of severe refractory asthma.严重难治性哮喘的患病率。
J Allergy Clin Immunol. 2015 Apr;135(4):896-902. doi: 10.1016/j.jaci.2014.08.042. Epub 2014 Oct 16.
9
Bronchial thermoplasty for moderate or severe persistent asthma in adults.成人中重度持续性哮喘的支气管热成形术
Cochrane Database Syst Rev. 2014 Mar 3;2014(3):CD009910. doi: 10.1002/14651858.CD009910.pub2.