K V Apoorva, Multani Mankirat, Shenoy S Vijendra, Sreeram Saraswathy, Kudlu Kshithi, Reddy Nayanika
Department of Otorhinolaryngology and Head & Neck Surgery, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, 576104 India.
Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, 576104 India.
Indian J Otolaryngol Head Neck Surg. 2025 May;77(5):2168-2172. doi: 10.1007/s12070-025-05463-y. Epub 2025 Apr 10.
Schwannomas are benign, well-encapsulated, slow-growing nerve sheath tumours composed exclusively of Schwann cells. Ancient schwannomas, a rare variant, are particularly uncommon in the head and neck region, with very few cases reported in the nasal cavity and paranasal sinuses. Here, we describe a case of a 35-year-old male who presented to our otorhinolaryngology department with complaints of right-sided nasal obstruction for the past four years. Imaging demonstrated a lesion with dimensions of 53 × 31 × 46 mm located within the right nasal cavity, involving the middle and inferior turbinate, resulting in expansion of the right osteo-meatal complex, and protruding into the maxillary antrum with thickening of the mucosa. The excision of the lesion was performed using an external approach medial maxillectomy; subsequent histological analysis unveiled the presence of an ancient schwannoma. A comprehensive analysis of existing literature was conducted, focusing on the diagnosis and treatment of this uncommon pathological entity.
施万细胞瘤是一种良性、包膜完整、生长缓慢的神经鞘瘤,仅由施万细胞组成。古老型施万细胞瘤是一种罕见的变异型,在头颈部尤为少见,鼻腔和鼻窦报道的病例极少。在此,我们描述一例35岁男性患者,因右侧鼻塞4年就诊于我们的耳鼻喉科。影像学检查显示右侧鼻腔内有一个大小为53×31×46mm的病变,累及中鼻甲和下鼻甲,导致右侧骨-鼻窦复合体扩大,并突入上颌窦,黏膜增厚。采用上颌骨内侧切除术的外部入路切除病变;随后的组织学分析显示存在古老型施万细胞瘤。我们对现有文献进行了全面分析,重点关注这种罕见病理实体的诊断和治疗。