Rex C, Kesavram A, Harishkumar M, Ganesh S Amudha, Kalaivani G, Premanand C
Rex Ortho Hospital, Coimbatore, Tamilnadu 641002 India.
PSG IMS-R, Coimbatore, Tamilnadu 641004 India.
Indian J Orthop. 2025 Mar 21;59(5):644-649. doi: 10.1007/s43465-025-01360-2. eCollection 2025 May.
Diagnosis of Seronegative Rheumatoid Arthritis (SNRA) is based on clinical, radiological, and MRI findings with set criteria. High specificity is provided by plain X-rays in the differential diagnosis of rheumatic disorders Blum A et al. in Journal de Radiologie 90(12):1789-17811, 2009, https://doi.org/10.1016/s0221-0363(09)73586-3. In our study of pelvis X-rays, we found that ischiopubic ramus enthesopathy was more common than sacroiliitis and we have coined that enthesopathy finding as "hanging drop sign" because of its characteristic appearance.
A total of 152 proven (92 Females, 60 Males) SNRA cases (based on ACR*/EULARcriteria and ASAS*criteria) were studied for enthesopathy features in their plain X-ray of pelvis. In addition to sacroiliitis, calcification/ossification of attachment of pelvic muscle and ligaments was documented. Hanging drop enthesopathy was noted in ischiopubic ramus in most of the cases. A cadaveric study was done on 10 specimens just to understand the corresponding anatomical origin of this enthesopathy.
Of the 152 pelvic radiographs studied, 110 revealed radiological evidence of SNRA. Among them, 64 patients had hanging drop sign (58.18%), 25 patients had sacroiliitis (22.72%), and 21 patients had other features like hip arthritis, calcifications around greater trochanter, iliac crest, and acetabular region. The cadaveric study revealed that the hanging drop sign corresponds to the adductor part of adductor magnus muscle and gracilis muscle origin in the ischiopubic ramus.
In pelvic radiology, hanging drop sign is a common radiological finding in patients with seronegative rheumatism. It is along the origin of adductor part of adductor magnus and gracilis. It is more common than sacroiliitis and this radiological feature can be a useful tool to diagnose SNRA.
血清阴性类风湿关节炎(SNRA)的诊断基于临床、放射学及MRI检查结果和既定标准。在风湿性疾病的鉴别诊断中,普通X线具有较高的特异性(Blum A等人,《放射学杂志》90(12):1789 - 17811, 2009, https://doi.org/10.1016/s0221-0363(09)73586-3)。在我们对骨盆X线的研究中,发现耻骨支附着点病比骶髂关节炎更常见,并且由于其特征性表现,我们将这种附着点病表现称为“垂滴征”。
共研究了152例经证实的(92例女性,60例男性)SNRA病例(基于美国风湿病学会(ACR*)/欧洲抗风湿病联盟(EULAR**)标准及脊柱关节炎国际学会(ASAS***)标准),观察其骨盆普通X线片上的附着点病特征。除了骶髂关节炎外,还记录了骨盆肌肉和韧带附着处的钙化/骨化情况。大多数病例中,耻骨支可见垂滴状附着点病。对10个标本进行了尸体研究,以了解这种附着点病的相应解剖学起源。
在研究的152张骨盆X线片中,110张显示有SNRA的放射学证据。其中,64例患者有垂滴征(58.18%),25例患者有骶髂关节炎(22.72%),21例患者有其他特征,如髋关节炎、大转子周围、髂嵴和髋臼区域的钙化。尸体研究显示,垂滴征对应于耻骨支处大收肌和股薄肌内收部分的起源。
在骨盆放射学中,垂滴征是血清阴性风湿病患者常见的放射学表现。它位于大收肌和股薄肌内收部分的起源处。它比骶髂关节炎更常见,这种放射学特征可作为诊断SNRA的有用工具。