Knopf P M, Linden T
J Parasitol. 1985 Aug;71(4):422-6.
The survival and maturation of Schistosoma mansoni worms was analyzed in normal, thyroidectomized (Thyrox), and hormone-restored Thyrox rats. Restoration therapy was conducted with both T3 and T4; weight gain of treated rats was monitored to assess hormone-replacement efficacy. Worm yields, lengths, and sex-ratios were compared. Egg yields and the capacity of miracidia to hatch from eggs were also analyzed. The results of these studies support the conclusion that the sequence of steps leading to completion of the S. mansoni life cycle are operational in Thyrox rats. Hormone-treated Thyrox rats are restored to the nonpermissive status, although the worms isolated from these rats still differ in certain respects when compared to worms isolated from normal rats.
在正常大鼠、甲状腺切除的大鼠（Thyrox）以及激素恢复的Thyrox大鼠中分析了曼氏血吸虫的存活和成熟情况。使用T3和T4进行恢复治疗；监测治疗大鼠的体重增加以评估激素替代疗效。比较了虫体产量、长度和性别比例。还分析了产卵量以及毛蚴从卵中孵化的能力。这些研究结果支持以下结论：导致曼氏血吸虫生命周期完成的步骤顺序在Thyrox大鼠中是有效的。激素治疗的Thyrox大鼠恢复到了非允许状态，尽管从这些大鼠中分离出的虫体与从正常大鼠中分离出的虫体相比在某些方面仍存在差异。
