Evron S, Yagel S, Samueloff A, Margaliot E, Burstein P, Sadovsky E
J Perinat Med. 1985;13(3):147-51.
Eleven cases of nonimmunologic hydrops fetalis occurring during a six year period were reviewed. The etiology of hydrops fetalis was established only in four cases. It included one case of endocardial fibrosis, two cases of non-immunologic hemolysis and one case of tachycardia. The pregnancies were complicated by polyhydramnios in 9 cases, preterm delivery in 10 cases, twins in 3 cases and pre-eclampsia in one case. Four of 11 fetuses died in utero, on one of them, intrauterine blood transfusion and administration of digoxin and furosemide was carried out. Five fetuses died neonatally and two survived. In one of the later cases, intravenous administration of digoxin with quinidine to the mother was without effect, nor did such treatment cause any effect on the neonate after delivery. Electric cardioversion supplemented with digoxin slowed the neonatal cardiac rhythm to normal range with later successful outcome. Earlier diagnosis by ultrasonography especially in cases of hydramnios and appropriate treatment are likely to improve this outcome.
回顾了六年期间发生的11例非免疫性胎儿水肿病例。仅在4例中确定了胎儿水肿的病因。其中包括1例心内膜纤维化、2例非免疫性溶血和1例心动过速。9例妊娠合并羊水过多，10例早产，3例双胎妊娠，1例先兆子痫。11例胎儿中有4例死于宫内，其中1例进行了宫内输血以及地高辛和速尿的给药。5例胎儿死于新生儿期，2例存活。在后来的1例病例中，给母亲静脉注射地高辛和奎尼丁无效，分娩后对新生儿也未产生任何影响。电复律加用地高辛使新生儿心律减慢至正常范围，随后获得成功结局。超声检查早期诊断，尤其是在羊水过多的病例中，以及适当的治疗可能会改善这种结局。
